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Year | Number of Results |
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Page 1
Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders.
J Neurochem. 2015 Dec;135(5):849-58. doi: 10.1111/jnc.13232. Epub 2015 Sep 3.
J Neurochem. 2015.
PMID: 26338675
Free article.
Review.
Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling.
Mediani L, Antoniani F, Galli V, Vinet J, Carrà AD, Bigi I, Tripathy V, Tiago T, Cimino M, Leo G, Amen T, Kaganovich D, Cereda C, Pansarasa O, Mandrioli J, Tripathi P, Troost D, Aronica E, Buchner J, Goswami A, Sterneckert J, Alberti S, Carra S.
Mediani L, et al. Among authors: bigi i.
EMBO Rep. 2021 May 5;22(5):e51740. doi: 10.15252/embr.202051740. Epub 2021 Mar 19.
EMBO Rep. 2021.
PMID: 33738926
Free PMC article.
Item in Clipboard
Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin.
Mediani L, Guillén-Boixet J, Vinet J, Franzmann TM, Bigi I, Mateju D, Carrà AD, Morelli FF, Tiago T, Poser I, Alberti S, Carra S.
Mediani L, et al. Among authors: bigi i.
EMBO J. 2019 Aug 1;38(15):e101341. doi: 10.15252/embj.2018101341. Epub 2019 Jul 4.
EMBO J. 2019.
PMID: 31271238
Free PMC article.
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BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes.
Mediani L, Galli V, Carrà AD, Bigi I, Vinet J, Ganassi M, Antoniani F, Tiago T, Cimino M, Mateju D, Cereda C, Pansarasa O, Alberti S, Mandrioli J, Carra S.
Mediani L, et al. Among authors: bigi i.
Cell Stress Chaperones. 2020 Nov;25(6):1045-1058. doi: 10.1007/s12192-020-01141-w. Epub 2020 Jul 21.
Cell Stress Chaperones. 2020.
PMID: 32696179
Free PMC article.
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A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.
Ganassi M, Mateju D, Bigi I, Mediani L, Poser I, Lee HO, Seguin SJ, Morelli FF, Vinet J, Leo G, Pansarasa O, Cereda C, Poletti A, Alberti S, Carra S.
Ganassi M, et al. Among authors: bigi i.
Mol Cell. 2016 Sep 1;63(5):796-810. doi: 10.1016/j.molcel.2016.07.021. Epub 2016 Aug 25.
Mol Cell. 2016.
PMID: 27570075
Free article.
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An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8.
Morelli FF, Mediani L, Heldens L, Bertacchini J, Bigi I, Carrà AD, Vinet J, Carra S.
Morelli FF, et al. Among authors: bigi i.
Cell Stress Chaperones. 2017 Jul;22(4):531-540. doi: 10.1007/s12192-017-0769-x. Epub 2017 Feb 8.
Cell Stress Chaperones. 2017.
PMID: 28181153
Free PMC article.
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The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Crippa V, Cicardi ME, Ramesh N, Seguin SJ, Ganassi M, Bigi I, Diacci C, Zelotti E, Baratashvili M, Gregory JM, Dobson CM, Cereda C, Pandey UB, Poletti A, Carra S.
Crippa V, et al. Among authors: bigi i.
Hum Mol Genet. 2016 Sep 15;25(18):3908-3924. doi: 10.1093/hmg/ddw232. Epub 2016 Jul 27.
Hum Mol Genet. 2016.
PMID: 27466192
Free PMC article.
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