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Aberrant L-Fucose Accumulation and Increased Core Fucosylation Are Metabolic Liabilities in Mesenchymal Glioblastoma.
Pieri V, Gallotti AL, Drago D, Cominelli M, Pagano I, Conti V, Valtorta S, Coliva A, Lago S, Michelatti D, Massimino L, Ungaro F, Perani L, Spinelli A, Castellano A, Falini A, Zippo A, Poliani PL, Moresco RM, Andolfo A, Galli R. Pieri V, et al. Among authors: pagano i. Cancer Res. 2023 Jan 18;83(2):195-218. doi: 10.1158/0008-5472.CAN-22-0677. Cancer Res. 2023. PMID: 36409826
mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma.
Conti V, Cominelli M, Pieri V, Gallotti AL, Pagano I, Zanella M, Mazzoleni S, Pivetta F, Patanè M, Scotti GM, Piras IS, Pollo B, Falini A, Zippo A, Castellano A, Maestro R, Poliani PL, Galli R. Conti V, et al. Among authors: pagano i. JCI Insight. 2021 Dec 8;6(23):e153462. doi: 10.1172/jci.insight.153462. JCI Insight. 2021. PMID: 34673573 Free PMC article.
Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.
Canu N, Pagano I, La Rosa LR, Pellegrino M, Ciotti MT, Mercanti D, Moretti F, Sposato V, Triaca V, Petrella C, Maruyama IN, Levi A, Calissano P. Canu N, et al. Among authors: pagano i. Front Mol Neurosci. 2017 Jan 31;10:15. doi: 10.3389/fnmol.2017.00015. eCollection 2017. Front Mol Neurosci. 2017. PMID: 28197073 Free PMC article.
Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity.
Nuzzo T, Feligioni M, Cristino L, Pagano I, Marcelli S, Iannuzzi F, Imperatore R, D'Angelo L, Petrella C, Carella M, Pollegioni L, Sacchi S, Punzo D, De Girolamo P, Errico F, Canu N, Usiello A. Nuzzo T, et al. Among authors: pagano i. Exp Neurol. 2019 Jul;317:51-65. doi: 10.1016/j.expneurol.2019.02.014. Epub 2019 Feb 26. Exp Neurol. 2019. PMID: 30822420