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Page 1
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Nat Immunol. 2020 Apr;21(4):381-387. doi: 10.1038/s41590-020-0621-9. Epub 2020 Mar 16.
Nat Immunol. 2020.
PMID: 32205881
Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation.
Tsakiri EN, Gumeni S, Iliaki KK, Benaki D, Vougas K, Sykiotis GP, Gorgoulis VG, Mikros E, Scorrano L, Trougakos IP.
Tsakiri EN, et al. Among authors: iliaki kk.
Aging Cell. 2019 Feb;18(1):e12845. doi: 10.1111/acel.12845. Epub 2018 Dec 10.
Aging Cell. 2019.
PMID: 30537423
Free PMC article.
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The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects.
Tsakiri EN, Gaboriaud-Kolar N, Iliaki KK, Tchoumtchoua J, Papanagnou ED, Chatzigeorgiou S, Tallas KD, Mikros E, Halabalaki M, Skaltsounis AL, Trougakos IP.
Tsakiri EN, et al. Among authors: iliaki kk.
Antioxid Redox Signal. 2017 Nov 10;27(14):1027-1047. doi: 10.1089/ars.2016.6910. Epub 2017 May 16.
Antioxid Redox Signal. 2017.
PMID: 28253732
Free PMC article.
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Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster.
Tsakiri EN, Iliaki KK, Höhn A, Grimm S, Papassideri IS, Grune T, Trougakos IP.
Tsakiri EN, et al. Among authors: iliaki kk.
Free Radic Biol Med. 2013 Dec;65:1155-1163. doi: 10.1016/j.freeradbiomed.2013.08.186. Epub 2013 Aug 30.
Free Radic Biol Med. 2013.
PMID: 23999505
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