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Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Ke YD, van Hummel A, Stevens CH, Gladbach A, Ippati S, Bi M, Lee WS, Krüger S, van der Hoven J, Volkerling A, Bongers A, Halliday G, Haass NK, Kiernan M, Delerue F, Ittner LM. Ke YD, et al. Among authors: ippati s. Acta Neuropathol. 2015 Nov;130(5):661-78. doi: 10.1007/s00401-015-1486-0. Epub 2015 Oct 5. Acta Neuropathol. 2015. PMID: 26437864
Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
van Hummel A, Chan G, van der Hoven J, Morsch M, Ippati S, Suh L, Bi M, Asih PR, Lee WS, Butler TA, Przybyla M, Halliday GM, Piguet O, Kiernan MC, Chung RS, Ittner LM, Ke YD. van Hummel A, et al. Among authors: ippati s. Am J Pathol. 2018 Jun;188(6):1447-1456. doi: 10.1016/j.ajpath.2018.03.002. Epub 2018 Mar 22. Am J Pathol. 2018. PMID: 29577934 Free article.
No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice.
van Hummel A, Bi M, Ippati S, van der Hoven J, Volkerling A, Lee WS, Tan DC, Bongers A, Ittner A, Ke YD, Ittner LM. van Hummel A, et al. Among authors: ippati s. PLoS One. 2016 Oct 13;11(10):e0163236. doi: 10.1371/journal.pone.0163236. eCollection 2016. PLoS One. 2016. PMID: 27736877 Free PMC article.
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.
Ittner A, Chua SW, Bertz J, Volkerling A, van der Hoven J, Gladbach A, Przybyla M, Bi M, van Hummel A, Stevens CH, Ippati S, Suh LS, Macmillan A, Sutherland G, Kril JJ, Silva AP, Mackay JP, Poljak A, Delerue F, Ke YD, Ittner LM. Ittner A, et al. Among authors: ippati s. Science. 2016 Nov 18;354(6314):904-908. doi: 10.1126/science.aah6205. Science. 2016. PMID: 27856911
Syntaxins 6 and 8 facilitate tau into secretory pathways.
Lee WS, Tan DC, Deng Y, van Hummel A, Ippati S, Stevens C, Carmona-Mora P, Ariawan D, Hou L, Stefen H, Tomanic T, Bi M, Tomasetig F, Martin A, Fath T, Palmer S, Ke YD, Ittner LM. Lee WS, et al. Among authors: ippati s. Biochem J. 2021 Apr 16;478(7):1471-1484. doi: 10.1042/BCJ20200664. Biochem J. 2021. PMID: 33769438 Free PMC article.
Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology.
Oggioni M, Mercurio D, Minuta D, Fumagalli S, Popiolek-Barczyk K, Sironi M, Ciechanowska A, Ippati S, De Blasio D, Perego C, Mika J, Garlanda C, De Simoni MG. Oggioni M, et al. Among authors: ippati s. Sci Rep. 2021 May 5;11(1):9616. doi: 10.1038/s41598-021-89032-7. Sci Rep. 2021. PMID: 33953334 Free PMC article.
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