Irving M - Search Results

1

VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding.

Lanitis E, Kosti P, Ronet C, Cribioli E, Rota G, Spill A, Reichenbach P, Zoete V, Dangaj Laniti D, Coukos G, Irving M. Lanitis E, et al. Among authors: irving m. J Immunother Cancer. 2021 Aug;9(8):e002151. doi: 10.1136/jitc-2020-002151. J Immunother Cancer. 2021. PMID: 34389616 Free PMC article.

2

MM-GBSA binding free energy decomposition and T cell receptor engineering.

Zoete V, Irving MB, Michielin O. Zoete V, et al. Among authors: irving mb. J Mol Recognit. 2010 Mar-Apr;23(2):142-52. doi: 10.1002/jmr.1005. J Mol Recognit. 2010. PMID: 20151417 Review.

3

Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function.

Schmid DA, Irving MB, Posevitz V, Hebeisen M, Posevitz-Fejfar A, Sarria JC, Gomez-Eerland R, Thome M, Schumacher TN, Romero P, Speiser DE, Zoete V, Michielin O, Rufer N. Schmid DA, et al. Among authors: irving mb. J Immunol. 2010 May 1;184(9):4936-46. doi: 10.4049/jimmunol.1000173. Epub 2010 Mar 29. J Immunol. 2010. PMID: 20351194

4

TCRep 3D: an automated in silico approach to study the structural properties of TCR repertoires.

Leimgruber A, Ferber M, Irving M, Hussain-Kahn H, Wieckowski S, Derré L, Rufer N, Zoete V, Michielin O. Leimgruber A, et al. Among authors: irving m. PLoS One. 2011;6(10):e26301. doi: 10.1371/journal.pone.0026301. Epub 2011 Oct 28. PLoS One. 2011. PMID: 22053188 Free PMC article.

5

Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness.

Irving M, Zoete V, Hebeisen M, Schmid D, Baumgartner P, Guillaume P, Romero P, Speiser D, Luescher I, Rufer N, Michielin O. Irving M, et al. J Biol Chem. 2012 Jun 29;287(27):23068-78. doi: 10.1074/jbc.M112.357673. Epub 2012 May 1. J Biol Chem. 2012. PMID: 22549784 Free PMC article.

6

Structure-Based, Rational Design of T Cell Receptors.

Zoete V, Irving M, Ferber M, Cuendet MA, Michielin O. Zoete V, et al. Among authors: irving m. Front Immunol. 2013 Sep 12;4:268. doi: 10.3389/fimmu.2013.00268. Front Immunol. 2013. PMID: 24062738 Free PMC article. Review.

7

T cells bearing a chimeric antigen receptor against prostate-specific membrane antigen mediate vascular disruption and result in tumor regression.

Santoro SP, Kim S, Motz GT, Alatzoglou D, Li C, Irving M, Powell DJ Jr, Coukos G. Santoro SP, et al. Among authors: irving m. Cancer Immunol Res. 2015 Jan;3(1):68-84. doi: 10.1158/2326-6066.CIR-14-0192. Epub 2014 Oct 30. Cancer Immunol Res. 2015. PMID: 25358763 Free PMC article.

8

Targeting the tumor vasculature to enhance T cell activity.

Lanitis E, Irving M, Coukos G. Lanitis E, et al. Among authors: irving m. Curr Opin Immunol. 2015 Apr;33:55-63. doi: 10.1016/j.coi.2015.01.011. Epub 2015 Feb 6. Curr Opin Immunol. 2015. PMID: 25665467 Free PMC article. Review.

9

1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).

Röhrig UF, Majjigapu SR, Caldelari D, Dilek N, Reichenbach P, Ascencao K, Irving M, Coukos G, Vogel P, Zoete V, Michielin O. Röhrig UF, et al. Among authors: irving m. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4330-3. doi: 10.1016/j.bmcl.2016.07.031. Epub 2016 Jul 16. Bioorg Med Chem Lett. 2016. PMID: 27469130

10

Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the Fuel.

Irving M, Vuillefroy de Silly R, Scholten K, Dilek N, Coukos G. Irving M, et al. Front Immunol. 2017 Apr 3;8:267. doi: 10.3389/fimmu.2017.00267. eCollection 2017. Front Immunol. 2017. PMID: 28421069 Free PMC article. Review.

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