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CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer's disease pathology.
Su W, Saravia J, Risch I, Rankin S, Guy C, Chapman NM, Shi H, Sun Y, Kc A, Li W, Huang H, Lim SA, Hu H, Wang Y, Liu D, Jiao Y, Chen PC, Soliman H, Yan KK, Zhang J, Vogel P, Liu X, Serrano GE, Beach TG, Yu J, Peng J, Chi H. Su W, et al. Among authors: risch i. Nat Immunol. 2023 Oct;24(10):1735-1747. doi: 10.1038/s41590-023-01604-z. Epub 2023 Sep 7. Nat Immunol. 2023. PMID: 37679549
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity.
Long L, Wei J, Lim SA, Raynor JL, Shi H, Connelly JP, Wang H, Guy C, Xie B, Chapman NM, Fu G, Wang Y, Huang H, Su W, Saravia J, Risch I, Wang YD, Li Y, Niu M, Dhungana Y, Kc A, Zhou P, Vogel P, Yu J, Pruett-Miller SM, Peng J, Chi H. Long L, et al. Among authors: risch i. Nature. 2021 Dec;600(7888):308-313. doi: 10.1038/s41586-021-04109-7. Epub 2021 Nov 18. Nature. 2021. PMID: 34795452 Free PMC article.
NetBID2 provides comprehensive hidden driver analysis.
Dong X, Ding L, Thrasher A, Wang X, Liu J, Pan Q, Rash J, Dhungana Y, Yang X, Risch I, Li Y, Yan L, Rusch M, McLeod C, Yan KK, Peng J, Chi H, Zhang J, Yu J. Dong X, et al. Among authors: risch i. Nat Commun. 2023 May 4;14(1):2581. doi: 10.1038/s41467-023-38335-6. Nat Commun. 2023. PMID: 37142594 Free PMC article.
PTEN directs developmental and metabolic signaling for innate-like T cell fate and tissue homeostasis.
Blanco DB, Chapman NM, Raynor JL, Xu C, Su W, Kc A, Li W, Lim SA, Schattgen S, Shi H, Risch I, Sun Y, Dhungana Y, Kim Y, Wei J, Rankin S, Neale G, Thomas PG, Yang K, Chi H. Blanco DB, et al. Among authors: risch i. Nat Cell Biol. 2022 Nov;24(11):1642-1654. doi: 10.1038/s41556-022-01011-w. Epub 2022 Oct 27. Nat Cell Biol. 2022. PMID: 36302969 Free PMC article.
Integrome signatures of lentiviral gene therapy for SCID-X1 patients.
Yan KK, Condori J, Ma Z, Metais JY, Ju B, Ding L, Dhungana Y, Palmer LE, Langfitt DM, Ferrara F, Throm R, Shi H, Risch I, Bhatara S, Shaner B, Lockey TD, Talleur AC, Easton J, Meagher MM, Puck JM, Cowan MJ, Zhou S, Mamcarz E, Gottschalk S, Yu J. Yan KK, et al. Among authors: risch i. Sci Adv. 2023 Oct 6;9(40):eadg9959. doi: 10.1126/sciadv.adg9959. Epub 2023 Oct 6. Sci Adv. 2023. PMID: 37801507 Free PMC article.