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Page 1
Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism.
Rheumatology (Oxford). 2020 May 1;59(5):1148-1158. doi: 10.1093/rheumatology/kez587.
Rheumatology (Oxford). 2020.
PMID: 31846032
Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer.
Dewi DL, Mohapatra SR, Blanco Cabañes S, Adam I, Somarribas Patterson LF, Berdel B, Kahloon M, Thürmann L, Loth S, Heilmann K, Weichenhan D, Mücke O, Heiland I, Wimberger P, Kuhlmann JD, Kellner KH, Schott S, Plass C, Platten M, Gerhäuser C, Trump S, Opitz CA.
Dewi DL, et al. Among authors: adam i.
Oncoimmunology. 2017 Jan 3;6(2):e1274477. doi: 10.1080/2162402X.2016.1274477. eCollection 2017.
Oncoimmunology. 2017.
PMID: 28344890
Free PMC article.
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Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation.
Adam I, Dewi DL, Mooiweer J, Sadik A, Mohapatra SR, Berdel B, Keil M, Sonner JK, Thedieck K, Rose AJ, Platten M, Heiland I, Trump S, Opitz CA.
Adam I, et al.
Oncoimmunology. 2018 Sep 5;7(12):e1486353. doi: 10.1080/2162402X.2018.1486353. eCollection 2018.
Oncoimmunology. 2018.
PMID: 30524887
Free PMC article.
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Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.
Tykocinski LO, Lauffer AM, Bohnen A, Kaul NC, Krienke S, Tretter T, Adam I, Mohapatra SR, Saikali P, Löhning M, Neidhart M, Gay S, Oezen I, Platten M, Opitz CA, Lorenz HM.
Tykocinski LO, et al. Among authors: adam i.
J Immunol. 2017 Apr 15;198(8):3109-3117. doi: 10.4049/jimmunol.1600600. Epub 2017 Mar 6.
J Immunol. 2017.
PMID: 28264972
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The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.
Nikolova T, Dvorak M, Jung F, Adam I, Krämer E, Gerhold-Ay A, Kaina B.
Nikolova T, et al. Among authors: adam i.
Toxicol Sci. 2014 Jul;140(1):103-17. doi: 10.1093/toxsci/kfu066. Epub 2014 Apr 17.
Toxicol Sci. 2014.
PMID: 24743697
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The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.
Sonner JK, Deumelandt K, Ott M, Thomé CM, Rauschenbach KJ, Schulz S, Munteanu B, Mohapatra S, Adam I, Hofer AC, Feuerer M, Opitz CA, Hopf C, Wick W, Platten M.
Sonner JK, et al. Among authors: adam i.
Oncoimmunology. 2016 Nov 15;5(12):e1240858. doi: 10.1080/2162402X.2016.1240858. eCollection 2016.
Oncoimmunology. 2016.
PMID: 28123877
Free PMC article.
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