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Page 1
Targeting Tyrosine Kinases in Acute Myeloid Leukemia: Why, Who and How?
Fernandez S, Desplat V, Villacreces A, Guitart AV, Milpied N, Pigneux A, Vigon I, Pasquet JM, Dumas PY. Fernandez S, et al. Among authors: vigon i. Int J Mol Sci. 2019 Jul 12;20(14):3429. doi: 10.3390/ijms20143429. Int J Mol Sci. 2019. PMID: 31336846 Free PMC article. Review.
Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells.
Dupont M, Huart M, Lauvinerie C, Bidet A, Guitart AV, Villacreces A, Vigon I, Desplat V, El Habhab A, Pigneux A, Ivanovic Z, Brunet De la Grange P, Dumas PY, Pasquet JM. Dupont M, et al. Among authors: vigon i. Cancers (Basel). 2022 Jan 17;14(2):453. doi: 10.3390/cancers14020453. Cancers (Basel). 2022. PMID: 35053612 Free PMC article.
Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL.
Dumas PY, Naudin C, Martin-Lannerée S, Izac B, Casetti L, Mansier O, Rousseau B, Artus A, Dufossée M, Giese A, Dubus P, Pigneux A, Praloran V, Bidet A, Villacreces A, Guitart A, Milpied N, Kosmider O, Vigon I, Desplat V, Dusanter-Fourt I, Pasquet JM. Dumas PY, et al. Among authors: vigon i. Haematologica. 2019 Oct;104(10):2017-2027. doi: 10.3324/haematol.2018.205385. Epub 2019 Mar 28. Haematologica. 2019. PMID: 30923103 Free PMC article. Clinical Trial.
Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia.
Dumas PY, Villacreces A, Guitart AV, El-Habhab A, Massara L, Mansier O, Bidet A, Martineau D, Fernandez S, Leguay T, Pigneux A, Vigon I, Pasquet JM, Desplat V. Dumas PY, et al. Among authors: vigon i. Clin Cancer Res. 2021 Nov 1;27(21):6012-6025. doi: 10.1158/1078-0432.CCR-20-3114. Epub 2021 Aug 16. Clin Cancer Res. 2021. PMID: 34400415
Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence.
Ianniciello A, Dumas PY, Drullion C, Guitart A, Villacreces A, Peytour Y, Chevaleyre J, Brunet de la Grange P, Vigon I, Desplat V, Priault M, Sbarba PD, Ivanovic Z, Mahon FX, Pasquet JM. Ianniciello A, et al. Among authors: vigon i. Oncotarget. 2017 Jun 30;8(57):96984-96992. doi: 10.18632/oncotarget.18904. eCollection 2017 Nov 14. Oncotarget. 2017. PMID: 29228587 Free PMC article.
11 results