Isacchi A - Search Results

1

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death.

Magnaghi P, D'Alessio R, Valsasina B, Avanzi N, Rizzi S, Asa D, Gasparri F, Cozzi L, Cucchi U, Orrenius C, Polucci P, Ballinari D, Perrera C, Leone A, Cervi G, Casale E, Xiao Y, Wong C, Anderson DJ, Galvani A, Donati D, O'Brien T, Jackson PK, Isacchi A. Magnaghi P, et al. Among authors: isacchi a. Nat Chem Biol. 2013 Sep;9(9):548-56. doi: 10.1038/nchembio.1313. Epub 2013 Jul 28. Nat Chem Biol. 2013. PMID: 23892893

2

Role of the Src homology 2 domains and interdomain regions in ZAP-70 phosphorylation and enzymatic activity.

Magistrelli G, Bosotti R, Valsasina B, Visco C, Perego R, Toma S, Acuto O, Isacchi A. Magistrelli G, et al. Among authors: isacchi a. Eur J Biochem. 1999 Dec;266(3):1166-73. doi: 10.1046/j.1432-1327.1999.00973.x. Eur J Biochem. 1999. PMID: 10583414 Free article.

3

Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylase.

Breton J, Avanzi N, Magagnin S, Covini N, Magistrelli G, Cozzi L, Isacchi A. Breton J, et al. Among authors: isacchi a. Eur J Biochem. 2000 Feb;267(4):1092-9. doi: 10.1046/j.1432-1327.2000.01104.x. Eur J Biochem. 2000. PMID: 10672018 Free article.

4

Thermodynamics of the high-affinity interaction of TCF4 with beta-catenin.

Knapp S, Zamai M, Volpi D, Nardese V, Avanzi N, Breton J, Plyte S, Flocco M, Marconi M, Isacchi A, Caiolfa VR. Knapp S, et al. Among authors: isacchi a. J Mol Biol. 2001 Mar 9;306(5):1179-89. doi: 10.1006/jmbi.2001.4463. J Mol Biol. 2001. PMID: 11237626

5

A new approach to phosphoserine and phosphothreonine analysis in peptides and proteins: chemical modification, enrichment via solid-phase reversible binding, and analysis by mass spectrometry.

Thaler F, Valsasina B, Baldi R, Xie J, Stewart A, Isacchi A, Kalisz HM, Rusconi L. Thaler F, et al. Among authors: isacchi a. Anal Bioanal Chem. 2003 Jun;376(3):366-73. doi: 10.1007/s00216-003-1919-9. Epub 2003 May 7. Anal Bioanal Chem. 2003. PMID: 12734628

6

Inhibitor affinity chromatography: profiling the specific reactivity of the proteome with immobilized molecules.

Lolli G, Thaler F, Valsasina B, Roletto F, Knapp S, Uggeri M, Bachi A, Matafora V, Storici P, Stewart A, Kalisz HM, Isacchi A. Lolli G, et al. Among authors: isacchi a. Proteomics. 2003 Jul;3(7):1287-98. doi: 10.1002/pmic.200300431. Proteomics. 2003. PMID: 12872229

7

3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding.

Pevarello P, Brasca MG, Amici R, Orsini P, Traquandi G, Corti L, Piutti C, Sansonna P, Villa M, Pierce BS, Pulici M, Giordano P, Martina K, Fritzen EL, Nugent RA, Casale E, Cameron A, Ciomei M, Roletto F, Isacchi A, Fogliatto G, Pesenti E, Pastori W, Marsiglio A, Leach KL, Clare PM, Fiorentini F, Varasi M, Vulpetti A, Warpehoski MA. Pevarello P, et al. Among authors: isacchi a. J Med Chem. 2004 Jun 17;47(13):3367-80. doi: 10.1021/jm031145u. J Med Chem. 2004. PMID: 15189033

8

Kinase selectivity profiling by inhibitor affinity chromatography.

Valsasina B, Kalisz HM, Isacchi A. Valsasina B, et al. Among authors: isacchi a. Expert Rev Proteomics. 2004 Oct;1(3):303-15. doi: 10.1586/14789450.1.3.303. Expert Rev Proteomics. 2004. PMID: 15966827 Review.

9

Searching for biomarkers of Aurora-A kinase activity: identification of in vitro substrates through a modified KESTREL approach.

Troiani S, Uggeri M, Moll J, Isacchi A, Kalisz HM, Rusconi L, Valsasina B. Troiani S, et al. Among authors: isacchi a. J Proteome Res. 2005 Jul-Aug;4(4):1296-303. doi: 10.1021/pr050018e. J Proteome Res. 2005. PMID: 16083279

10

Crystal structure of the T315I Abl mutant in complex with the aurora kinases inhibitor PHA-739358.

Modugno M, Casale E, Soncini C, Rosettani P, Colombo R, Lupi R, Rusconi L, Fancelli D, Carpinelli P, Cameron AD, Isacchi A, Moll J. Modugno M, et al. Among authors: isacchi a. Cancer Res. 2007 Sep 1;67(17):7987-90. doi: 10.1158/0008-5472.CAN-07-1825. Cancer Res. 2007. PMID: 17804707

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