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18F-Trifluoromethanesulfinate Enables Direct C-H 18F-Trifluoromethylation of Native Aromatic Residues in Peptides.
Kee CW, Tack O, Guibbal F, Wilson TC, Isenegger PG, Imiołek M, Verhoog S, Tilby M, Boscutti G, Ashworth S, Chupin J, Kashani R, Poh AWJ, Sosabowski JK, Macholl S, Plisson C, Cornelissen B, Willis MC, Passchier J, Davis BG, Gouverneur V. Kee CW, et al. Among authors: isenegger pg. J Am Chem Soc. 2020 Jan 22;142(3):1180-1185. doi: 10.1021/jacs.9b11709. Epub 2020 Jan 13. J Am Chem Soc. 2020. PMID: 31913613 Free PMC article.
Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib.
Guibbal F, Isenegger PG, Wilson TC, Pacelli A, Mahaut D, Sap JBI, Taylor NJ, Verhoog S, Preshlock S, Hueting R, Cornelissen B, Gouverneur V. Guibbal F, et al. Among authors: isenegger pg. Nat Protoc. 2020 Apr;15(4):1525-1541. doi: 10.1038/s41596-020-0295-7. Epub 2020 Feb 28. Nat Protoc. 2020. PMID: 32111986
Light-driven post-translational installation of reactive protein side chains.
Josephson B, Fehl C, Isenegger PG, Nadal S, Wright TH, Poh AWJ, Bower BJ, Giltrap AM, Chen L, Batchelor-McAuley C, Roper G, Arisa O, Sap JBI, Kawamura A, Baldwin AJ, Mohammed S, Compton RG, Gouverneur V, Davis BG. Josephson B, et al. Among authors: isenegger pg. Nature. 2020 Sep;585(7826):530-537. doi: 10.1038/s41586-020-2733-7. Epub 2020 Sep 23. Nature. 2020. PMID: 32968259
Post-translational insertion of boron in proteins to probe and modulate function.
Mollner TA, Isenegger PG, Josephson B, Buchanan C, Lercher L, Oehlrich D, Hansen DF, Mohammed S, Baldwin AJ, Gouverneur V, Davis BG. Mollner TA, et al. Among authors: isenegger pg. Nat Chem Biol. 2021 Dec;17(12):1245-1261. doi: 10.1038/s41589-021-00883-7. Epub 2021 Nov 1. Nat Chem Biol. 2021. PMID: 34725511 Free PMC article.
15 results