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Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease.
Fujimaki M, Saiki S, Li Y, Kaga N, Taka H, Hatano T, Ishikawa KI, Oji Y, Mori A, Okuzumi A, Koinuma T, Ueno SI, Imamichi Y, Ueno T, Miura Y, Funayama M, Hattori N. Fujimaki M, et al. Among authors: ishikawa ki. Neurology. 2018 Jan 30;90(5):e404-e411. doi: 10.1212/WNL.0000000000004888. Epub 2018 Jan 3. Neurology. 2018. PMID: 29298852 Free PMC article.
Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBS.
Ogaki K, Li Y, Takanashi M, Ishikawa K, Kobayashi T, Nonaka T, Hasegawa M, Kishi M, Yoshino H, Funayama M, Tsukamoto T, Shioya K, Yokochi M, Imai H, Sasaki R, Kokubo Y, Kuzuhara S, Motoi Y, Tomiyama H, Hattori N. Ogaki K, et al. Parkinsonism Relat Disord. 2013 Jan;19(1):15-20. doi: 10.1016/j.parkreldis.2012.06.019. Epub 2012 Jul 18. Parkinsonism Relat Disord. 2013. PMID: 22818528
Ethambutol neutralizes lysosomes and causes lysosomal zinc accumulation.
Yamada D, Saiki S, Furuya N, Ishikawa K, Imamichi Y, Kambe T, Fujimura T, Ueno T, Koike M, Sumiyoshi K, Hattori N. Yamada D, et al. Biochem Biophys Res Commun. 2016 Feb 26;471(1):109-16. doi: 10.1016/j.bbrc.2016.01.171. Epub 2016 Feb 4. Biochem Biophys Res Commun. 2016. PMID: 26851368 Free article.
Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease.
Ren Q, Ma M, Yang J, Nonaka R, Yamaguchi A, Ishikawa KI, Kobayashi K, Murayama S, Hwang SH, Saiki S, Akamatsu W, Hattori N, Hammock BD, Hashimoto K. Ren Q, et al. Among authors: ishikawa ki. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5815-E5823. doi: 10.1073/pnas.1802179115. Epub 2018 May 7. Proc Natl Acad Sci U S A. 2018. PMID: 29735655 Free PMC article.
51 results