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In situ snapshots along a mammalian selective autophagy pathway.
Li M, Tripathi-Giesgen I, Schulman BA, Baumeister W, Wilfling F. Li M, et al. Among authors: tripathi giesgen i. Proc Natl Acad Sci U S A. 2023 Mar 21;120(12):e2221712120. doi: 10.1073/pnas.2221712120. Epub 2023 Mar 14. Proc Natl Acad Sci U S A. 2023. PMID: 36917659 Free PMC article.
Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Li J, Purser N, Liwocha J, Scott DC, Byers HA, Steigenberger B, Hill S, Tripathi-Giesgen I, Hinkle T, Hansen FM, Prabu JR, Radhakrishnan SK, Kirkpatrick DS, Reichermeier KM, Schulman BA, Kleiger G. Li J, et al. Among authors: tripathi giesgen i. Mol Cell. 2024 Apr 4;84(7):1304-1320.e16. doi: 10.1016/j.molcel.2024.01.022. Epub 2024 Feb 20. Mol Cell. 2024. PMID: 38382526 Free PMC article.
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Horn-Ghetko D, Hopf LVM, Tripathi-Giesgen I, Du J, Kostrhon S, Vu DT, Beier V, Steigenberger B, Prabu JR, Stier L, Bruss EM, Mann M, Xiong Y, Schulman BA. Horn-Ghetko D, et al. Among authors: tripathi giesgen i. Nat Struct Mol Biol. 2024 Apr 11. doi: 10.1038/s41594-024-01257-y. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38605244