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Sirt1 counteracts decrease in membrane phospholipid unsaturation and diastolic dysfunction during saturated fatty acid overload.
Yamamoto T, Endo J, Kataoka M, Matsuhashi T, Katsumata Y, Shirakawa K, Yoshida N, Isobe S, Moriyama H, Goto S, Yamashita K, Ohto-Nakanishi T, Nakanishi H, Shimanaka Y, Kono N, Shinmura K, Arai H, Fukuda K, Sano M. Yamamoto T, et al. Among authors: isobe s. J Mol Cell Cardiol. 2019 Aug;133:1-11. doi: 10.1016/j.yjmcc.2019.05.019. Epub 2019 May 27. J Mol Cell Cardiol. 2019. PMID: 31145942
Decrease in membrane phospholipids unsaturation correlates with myocardial diastolic dysfunction.
Yamamoto T, Endo J, Kataoka M, Matsuhashi T, Katsumata Y, Shirakawa K, Yoshida N, Isobe S, Moriyama H, Goto S, Yamashita K, Nakanishi H, Shimanaka Y, Kono N, Shinmura K, Arai H, Fukuda K, Sano M. Yamamoto T, et al. Among authors: isobe s. PLoS One. 2018 Dec 11;13(12):e0208396. doi: 10.1371/journal.pone.0208396. eCollection 2018. PLoS One. 2018. PMID: 30533011 Free PMC article.
Pressure overload inhibits glucocorticoid receptor transcriptional activity in cardiomyocytes and promotes pathological cardiac hypertrophy.
Matsuhashi T, Endo J, Katsumata Y, Yamamoto T, Shimizu N, Yoshikawa N, Kataoka M, Isobe S, Moriyama H, Goto S, Fukuda K, Tanaka H, Sano M. Matsuhashi T, et al. Among authors: isobe s. J Mol Cell Cardiol. 2019 May;130:122-130. doi: 10.1016/j.yjmcc.2019.03.019. Epub 2019 Apr 1. J Mol Cell Cardiol. 2019. PMID: 30946837
Adrenal cortex hypoxia modulates aldosterone production in heart failure.
Yamashita K, Ito K, Endo J, Matsuhashi T, Katsumata Y, Yamamoto T, Shirakawa K, Isobe S, Kataoka M, Yoshida N, Goto S, Moriyama H, Kitakata H, Mitani F, Fukuda K, Goda N, Ichihara A, Sano M. Yamashita K, et al. Among authors: isobe s. Biochem Biophys Res Commun. 2020 Mar 26;524(1):184-189. doi: 10.1016/j.bbrc.2020.01.088. Epub 2020 Jan 23. Biochem Biophys Res Commun. 2020. PMID: 31982132 Free article.
Palmitate induces cardiomyocyte death via inositol requiring enzyme-1 (IRE1)-mediated signaling independent of X-box binding protein 1 (XBP1).
Yamamoto T, Endo J, Kataoka M, Matsuhashi T, Katsumata Y, Shirakawa K, Isobe S, Moriyama H, Goto S, Shimanaka Y, Kono N, Arai H, Shinmura K, Fukuda K, Sano M. Yamamoto T, et al. Among authors: isobe s. Biochem Biophys Res Commun. 2020 May 21;526(1):122-127. doi: 10.1016/j.bbrc.2020.03.027. Epub 2020 Mar 19. Biochem Biophys Res Commun. 2020. PMID: 32199617 Free article.
Omega-3 fatty acid epoxides produced by PAF-AH2 in mast cells regulate pulmonary vascular remodeling.
Moriyama H, Endo J, Kataoka M, Shimanaka Y, Kono N, Sugiura Y, Goto S, Kitakata H, Hiraide T, Yoshida N, Isobe S, Yamamoto T, Shirakawa K, Anzai A, Katsumata Y, Suematsu M, Kosaki K, Fukuda K, Arai H, Sano M. Moriyama H, et al. Among authors: isobe s. Nat Commun. 2022 May 31;13(1):3013. doi: 10.1038/s41467-022-30621-z. Nat Commun. 2022. PMID: 35641514 Free PMC article.
Negative legacy of obesity.
Shirakawa K, Endo J, Katsumata Y, Yamamoto T, Kataoka M, Isobe S, Yoshida N, Fukuda K, Sano M. Shirakawa K, et al. Among authors: isobe s. PLoS One. 2017 Oct 26;12(10):e0186303. doi: 10.1371/journal.pone.0186303. eCollection 2017. PLoS One. 2017. PMID: 29073165 Free PMC article.
391 results