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Senolytic treatment reverses obesity-mediated senescent cell accumulation in the ovary.
Hense JD, Garcia DN, Isola JV, Alvarado-Rincón JA, Zanini BM, Prosczek JB, Stout MB, Mason JB, Walsh PT, Brieño-Enríquez MA, Schadock I, Barros CC, Masternak MM, Schneider A. Hense JD, et al. Among authors: isola jv. Geroscience. 2022 Jun;44(3):1747-1759. doi: 10.1007/s11357-022-00573-9. Epub 2022 Apr 23. Geroscience. 2022. PMID: 35460445 Free PMC article.
17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice.
Ali Mondal S, Sathiaseelan R, Mann SN, Kamal M, Luo W, Saccon TD, Isola JVV, Peelor FF 3rd, Li T, Freeman WM, Miller BF, Stout MB. Ali Mondal S, et al. Am J Physiol Endocrinol Metab. 2023 Feb 1;324(2):E120-E134. doi: 10.1152/ajpendo.00256.2022. Epub 2022 Dec 14. Am J Physiol Endocrinol Metab. 2023. PMID: 36516471 Free PMC article.
Senolytic treatment fails to improve ovarian reserve or fertility in female mice.
Garcia DN, Hense JD, Zanini BM, Isola JVV, Prosczek JB, Ashiqueali S, Oliveira TL, Mason JB, Schadock IC, Barros CC, Stout MB, Masternak MM, Schneider A. Garcia DN, et al. Among authors: isola jvv. Geroscience. 2024 Jun;46(3):3445-3455. doi: 10.1007/s11357-024-01089-0. Epub 2024 Feb 15. Geroscience. 2024. PMID: 38358579 Free PMC article.
A single-cell atlas of the aging mouse ovary.
Isola JVV, Ocañas SR, Hubbart CR, Ko S, Mondal SA, Hense JD, Carter HNC, Schneider A, Kovats S, Alberola-Ila J, Freeman WM, Stout MB. Isola JVV, et al. Nat Aging. 2024 Jan;4(1):145-162. doi: 10.1038/s43587-023-00552-5. Epub 2024 Jan 10. Nat Aging. 2024. PMID: 38200272 Free PMC article.
Role of Estrogen Receptor α in Aging and Chronic Disease.
Isola JVV, Ko S, Ocañas SR, Stout MB. Isola JVV, et al. Adv Geriatr Med Res. 2023;5(2):e230005. doi: 10.20900/agmr20230005. Epub 2023 Jun 6. Adv Geriatr Med Res. 2023. PMID: 37425648 Free PMC article.
Dasatinib and quercetin increase testosterone and sperm concentration in mice.
Garcia DN, Hense JD, Zanini BM, Isola JVV, Pradiee J, Prosczek JB, Alvarado-Rincón JA, Mondadori RG, Mason JB, Brieño-Enríquez MA, Barros CC, Stout MB, Masternak MM, Schneider A. Garcia DN, et al. Among authors: isola jvv. Physiol Int. 2023 May 26;110(2):121-134. doi: 10.1556/2060.2023.00192. Print 2023 Jun 12. Physiol Int. 2023. PMID: 37235453
A single-cell atlas of the aging murine ovary.
Isola JVV, Ocañas SR, Hubbart CR, Ko S, Mondal SA, Hense JD, Carter HNC, Schneider A, Kovats S, Alberola-Ila J, Freeman WM, Stout MB. Isola JVV, et al. bioRxiv [Preprint]. 2023 Sep 6:2023.04.29.538828. doi: 10.1101/2023.04.29.538828. bioRxiv. 2023. PMID: 37162983 Free PMC article. Updated. Preprint.
20 results