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Optimality in the development of intestinal crypts.
Itzkovitz S, Blat IC, Jacks T, Clevers H, van Oudenaarden A. Itzkovitz S, et al. Cell. 2012 Feb 3;148(3):608-19. doi: 10.1016/j.cell.2011.12.025. Cell. 2012. PMID: 22304925 Free PMC article.
Slug and Sox9 cooperatively determine the mammary stem cell state.
Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA. Guo W, et al. Among authors: itzkovitz s. Cell. 2012 Mar 2;148(5):1015-28. doi: 10.1016/j.cell.2012.02.008. Cell. 2012. PMID: 22385965 Free PMC article.
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.
van Es JH, Haegebarth A, Kujala P, Itzkovitz S, Koo BK, Boj SF, Korving J, van den Born M, van Oudenaarden A, Robine S, Clevers H. van Es JH, et al. Among authors: itzkovitz s. Mol Cell Biol. 2012 May;32(10):1918-27. doi: 10.1128/MCB.06288-11. Epub 2012 Mar 5. Mol Cell Biol. 2012. PMID: 22393260 Free PMC article.
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.
Muñoz J, Stange DE, Schepers AG, van de Wetering M, Koo BK, Itzkovitz S, Volckmann R, Kung KS, Koster J, Radulescu S, Myant K, Versteeg R, Sansom OJ, van Es JH, Barker N, van Oudenaarden A, Mohammed S, Heck AJ, Clevers H. Muñoz J, et al. Among authors: itzkovitz s. EMBO J. 2012 Jun 12;31(14):3079-91. doi: 10.1038/emboj.2012.166. EMBO J. 2012. PMID: 22692129 Free PMC article.
Single-molecule mRNA detection and counting in mammalian tissue.
Lyubimova A, Itzkovitz S, Junker JP, Fan ZP, Wu X, van Oudenaarden A. Lyubimova A, et al. Among authors: itzkovitz s. Nat Protoc. 2013 Sep;8(9):1743-58. doi: 10.1038/nprot.2013.109. Epub 2013 Aug 15. Nat Protoc. 2013. PMID: 23949380
Genetic and phenotypic diversity in breast tumor metastases.
Almendro V, Kim HJ, Cheng YK, Gönen M, Itzkovitz S, Argani P, van Oudenaarden A, Sukumar S, Michor F, Polyak K. Almendro V, et al. Among authors: itzkovitz s. Cancer Res. 2014 Mar 1;74(5):1338-48. doi: 10.1158/0008-5472.CAN-13-2357-T. Epub 2014 Jan 21. Cancer Res. 2014. PMID: 24448237 Free PMC article.
Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.
Almendro V, Cheng YK, Randles A, Itzkovitz S, Marusyk A, Ametller E, Gonzalez-Farre X, Muñoz M, Russnes HG, Helland A, Rye IH, Borresen-Dale AL, Maruyama R, van Oudenaarden A, Dowsett M, Jones RL, Reis-Filho J, Gascon P, Gönen M, Michor F, Polyak K. Almendro V, et al. Among authors: itzkovitz s. Cell Rep. 2014 Feb 13;6(3):514-27. doi: 10.1016/j.celrep.2013.12.041. Epub 2014 Jan 23. Cell Rep. 2014. PMID: 24462293 Free PMC article.
105 results