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2013 1
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Page 1
A new age of precision gene therapy.
Schambach A, Buchholz CJ, Torres-Ruiz R, Cichutek K, Morgan M, Trapani I, Büning H. Schambach A, et al. Among authors: trapani i. Lancet. 2024 Feb 10;403(10426):568-582. doi: 10.1016/S0140-6736(23)01952-9. Epub 2023 Nov 22. Lancet. 2024. PMID: 38006899 Review.
Inclusion of a degron reduces levelsof undesired inteins after AAV-mediated proteintrans-splicing in the retina.
Tornabene P, Trapani I, Centrulo M, Marrocco E, Minopoli R, Lupo M, Iodice C, Gesualdo C, Simonelli F, Surace EM, Auricchio A. Tornabene P, et al. Among authors: trapani i. Mol Ther Methods Clin Dev. 2021 Oct 19;23:448-459. doi: 10.1016/j.omtm.2021.10.004. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34786437 Free PMC article.
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance.
Naso F, Intartaglia D, Falanga D, Soldati C, Polishchuk E, Giamundo G, Tiberi P, Marrocco E, Scudieri P, Di Malta C, Trapani I, Nusco E, Salierno FG, Surace EM, Galietta LJ, Banfi S, Auricchio A, Ballabio A, Medina DL, Conte I. Naso F, et al. Among authors: trapani i. EMBO J. 2020 Apr 15;39(8):e102468. doi: 10.15252/embj.2019102468. Epub 2020 Mar 10. EMBO J. 2020. PMID: 32154600 Free PMC article.
Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina.
Tornabene P, Trapani I, Minopoli R, Centrulo M, Lupo M, de Simone S, Tiberi P, Dell'Aquila F, Marrocco E, Iodice C, Iuliano A, Gesualdo C, Rossi S, Giaquinto L, Albert S, Hoyng CB, Polishchuk E, Cremers FPM, Surace EM, Simonelli F, De Matteis MA, Polishchuk R, Auricchio A. Tornabene P, et al. Among authors: trapani i. Sci Transl Med. 2019 May 15;11(492):eaav4523. doi: 10.1126/scitranslmed.aav4523. Sci Transl Med. 2019. PMID: 31092694 Free PMC article.
Seeing the Light after 25 Years of Retinal Gene Therapy.
Trapani I, Auricchio A. Trapani I, et al. Trends Mol Med. 2018 Aug;24(8):669-681. doi: 10.1016/j.molmed.2018.06.006. Epub 2018 Jul 5. Trends Mol Med. 2018. PMID: 29983335 Free article. Review.
16 results