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Twice-daily dosing of esomeprazole effectively inhibits acid secretion in CYP2C19 rapid metabolisers compared with twice-daily omeprazole, rabeprazole or lansoprazole.
Sahara S, Sugimoto M, Uotani T, Ichikawa H, Yamade M, Iwaizumi M, Yamada T, Osawa S, Sugimoto K, Umemura K, Miyajima H, Furuta T. Sahara S, et al. Among authors: iwaizumi m. Aliment Pharmacol Ther. 2013 Nov;38(9):1129-37. doi: 10.1111/apt.12492. Epub 2013 Sep 16. Aliment Pharmacol Ther. 2013. PMID: 24099474 Free article. Clinical Trial.
Prospective study of daily low-dose nedaplatin and continuous 5-fluorouracil infusion combined with radiation for the treatment of esophageal squamous cell carcinoma.
Osawa S, Furuta T, Sugimoto K, Kosugi T, Terai T, Yamade M, Takayanagi Y, Nishino M, Hamaya Y, Kodaira C, Yamada T, Iwaizumi M, Takagaki K, Yoshida K, Kanaoka S, Ikuma M. Osawa S, et al. Among authors: iwaizumi m. BMC Cancer. 2009 Nov 22;9:408. doi: 10.1186/1471-2407-9-408. BMC Cancer. 2009. PMID: 19930599 Free PMC article. Clinical Trial.
Prevention of gastric mucosal injury induced by anti-platelet drugs by famotidine.
Uotani T, Sugimoto M, Nishino M, Ichikawa H, Sahara S, Yamade M, Iwaizumi M, Yamada T, Osawa S, Sugimoto K, Umemura K, Watanabe H, Miyajima H, Furuta T. Uotani T, et al. Among authors: iwaizumi m. J Clin Pharmacol. 2014 Aug;54(8):858-64. doi: 10.1002/jcph.284. Epub 2014 Mar 21. J Clin Pharmacol. 2014. PMID: 24615745 Clinical Trial.
One-day front-loading with four doses of rabeprazole followed by a standard twice-daily regimen provides sufficient acid inhibition in extensive metabolizers of CYP2C19.
Kagami T, Sugimoto M, Ichikawa H, Sahara S, Uotani T, Yamade M, Hamaya Y, Iwaizumi M, Osawa S, Sugimoto K, Miyajima H, Furuta T. Kagami T, et al. Among authors: iwaizumi m. Eur J Clin Pharmacol. 2015 Dec;71(12):1467-75. doi: 10.1007/s00228-015-1941-9. Epub 2015 Oct 2. Eur J Clin Pharmacol. 2015. PMID: 26427705 Clinical Trial.
113 results