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Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids In Vitro: A 3D Tumour Model for Pre-therapeutic Drug Screening.
Nörz D, Mullins CS, Smit DJ, Linnebacher M, Hagel G, Mirdogan A, Siekiera J, Ehm P, Izbicki JR, Block A, Thastrup O, Jücker M. Nörz D, et al. Among authors: jucker m. Anticancer Res. 2021 May;41(5):2257-2275. doi: 10.21873/anticanres.15002. Anticancer Res. 2021. PMID: 33952452
ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.
Kebenko M, Drenckhan A, Gros SJ, Jücker M, Grabinski N, Ewald F, Grottke A, Schultze A, Izbicki JR, Bokemeyer C, Wellbrock J, Fiedler W. Kebenko M, et al. Among authors: jucker m. Cell Signal. 2015 Feb;27(2):373-81. doi: 10.1016/j.cellsig.2014.11.022. Epub 2014 Nov 27. Cell Signal. 2015. PMID: 25435423
Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
Wellbrock J, Latuske E, Köhler J, Wagner K, Stamm H, Vettorazzi E, Vohwinkel G, Klokow M, Uibeleisen R, Ehm P, Riecken K, Loges S, Thol F, Schubert C, Amling M, Jücker M, Bokemeyer C, Heuser M, Krauter J, Fiedler W. Wellbrock J, et al. Among authors: jucker m. Clin Cancer Res. 2015 May 15;21(10):2388-98. doi: 10.1158/1078-0432.CCR-14-1059. Epub 2015 Mar 5. Clin Cancer Res. 2015. PMID: 25745035
COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.
Hofmann BT, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak AS, Harder S, El Gammal AT, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki JR, Jücker M, Bockhorn M, Wolters-Eisfeld G. Hofmann BT, et al. Among authors: jucker m. Mol Cancer. 2015 May 29;14:109. doi: 10.1186/s12943-015-0386-1. Mol Cancer. 2015. PMID: 26021314 Free PMC article.
351 results