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Year Number of Results
2015 1
2016 3
2017 1
2019 5
2020 8
2021 9
2022 7
2023 4
2024 2

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36 results

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Page 1
Neutrophils as potential therapeutic targets in hepatocellular carcinoma.
Geh D, Leslie J, Rumney R, Reeves HL, Bird TG, Mann DA. Geh D, et al. Among authors: leslie j. Nat Rev Gastroenterol Hepatol. 2022 Apr;19(4):257-273. doi: 10.1038/s41575-021-00568-5. Epub 2022 Jan 12. Nat Rev Gastroenterol Hepatol. 2022. PMID: 35022608 Review.
CXCR2 inhibition enables NASH-HCC immunotherapy.
Leslie J, Mackey JBG, Jamieson T, Ramon-Gil E, Drake TM, Fercoq F, Clark W, Gilroy K, Hedley A, Nixon C, Luli S, Laszczewska M, Pinyol R, Esteban-Fabró R, Willoughby CE, Haber PK, Andreu-Oller C, Rahbari M, Fan C, Pfister D, Raman S, Wilson N, Müller M, Collins A, Geh D, Fuller A, McDonald D, Hulme G, Filby A, Cortes-Lavaud X, Mohamed NE, Ford CA, Raffo Iraolagoitia XL, McFarlane AJ, McCain MV, Ridgway RA, Roberts EW, Barry ST, Graham GJ, Heikenwälder M, Reeves HL, Llovet JM, Carlin LM, Bird TG, Sansom OJ, Mann DA. Leslie J, et al. Gut. 2022 Apr 27;71(10):2093-106. doi: 10.1136/gutjnl-2021-326259. Online ahead of print. Gut. 2022. PMID: 35477863 Free PMC article.
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Chauhan A, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. Malehmir M, et al. Among authors: leslie j. Nat Med. 2019 Apr;25(4):641-655. doi: 10.1038/s41591-019-0379-5. Epub 2019 Apr 1. Nat Med. 2019. PMID: 30936549 Free article.
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma.
Hall Z, Chiarugi D, Charidemou E, Leslie J, Scott E, Pellegrinet L, Allison M, Mocciaro G, Anstee QM, Evan GI, Hoare M, Vidal-Puig A, Oakley F, Vacca M, Griffin JL. Hall Z, et al. Among authors: leslie j. Hepatology. 2021 Mar;73(3):1028-1044. doi: 10.1002/hep.31391. Epub 2020 Nov 3. Hepatology. 2021. PMID: 32460431
Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.
Lagnado A, Leslie J, Ruchaud-Sparagano MH, Victorelli S, Hirsova P, Ogrodnik M, Collins AL, Vizioli MG, Habiballa L, Saretzki G, Evans SA, Salmonowicz H, Hruby A, Geh D, Pavelko KD, Dolan D, Reeves HL, Grellscheid S, Wilson CH, Pandanaboyana S, Doolittle M, von Zglinicki T, Oakley F, Gallage S, Wilson CL, Birch J, Carroll B, Chapman J, Heikenwalder M, Neretti N, Khosla S, Masuda CA, Tchkonia T, Kirkland JL, Jurk D, Mann DA, Passos JF. Lagnado A, et al. Among authors: leslie j. EMBO J. 2021 May 3;40(9):e106048. doi: 10.15252/embj.2020106048. Epub 2021 Mar 25. EMBO J. 2021. PMID: 33764576 Free PMC article.
The exercise IL-6 enigma in cancer.
Orange ST, Leslie J, Ross M, Mann DA, Wackerhage H. Orange ST, et al. Among authors: leslie j. Trends Endocrinol Metab. 2023 Nov;34(11):749-763. doi: 10.1016/j.tem.2023.08.001. Epub 2023 Aug 24. Trends Endocrinol Metab. 2023. PMID: 37633799 Free article. Review.
A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis.
Garcia-Macia M, Santos-Ledo A, Leslie J, Paish HL, Collins AL, Scott RS, Watson A, Burgoyne RA, White S, French J, Hammond J, Borthwick LA, Mann J, Bolaños JP, Korolchuk VI, Oakley F, Mann DA. Garcia-Macia M, et al. Among authors: leslie j. Hepatology. 2021 Dec;74(6):3441-3459. doi: 10.1002/hep.32048. Epub 2021 Sep 21. Hepatology. 2021. PMID: 34233024 Free article.
Immunomodulatory Effects of Lenvatinib Plus Anti-Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular Carcinoma.
Torrens L, Montironi C, Puigvehí M, Mesropian A, Leslie J, Haber PK, Maeda M, Balaseviciute U, Willoughby CE, Abril-Fornaguera J, Piqué-Gili M, Torres-Martín M, Peix J, Geh D, Ramon-Gil E, Saberi B, Friedman SL, Mann DA, Sia D, Llovet JM. Torrens L, et al. Among authors: leslie j. Hepatology. 2021 Nov;74(5):2652-2669. doi: 10.1002/hep.32023. Epub 2021 Sep 27. Hepatology. 2021. PMID: 34157147 Free article.
Harnessing neutrophil plasticity for HCC immunotherapy.
Ramon-Gil E, Geh D, Leslie J. Ramon-Gil E, et al. Among authors: leslie j. Essays Biochem. 2023 Sep 28;67(6):941-955. doi: 10.1042/EBC20220245. Essays Biochem. 2023. PMID: 37534829 Free PMC article. Review.
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis.
Leslie J, Macia MG, Luli S, Worrell JC, Reilly WJ, Paish HL, Knox A, Barksby BS, Gee LM, Zaki MYW, Collins AL, Burgoyne RA, Cameron R, Bragg C, Xu X, Chung GW, Brown CDA, Blanchard AD, Nanthakumar CB, Karsdal M, Robinson SM, Manas DM, Sen G, French J, White SA, Murphy S, Trost M, Zakrzewski JL, Klein U, Schwabe RF, Mederacke I, Nixon C, Bird T, Teuwen LA, Schoonjans L, Carmeliet P, Mann J, Fisher AJ, Sheerin NS, Borthwick LA, Mann DA, Oakley F. Leslie J, et al. Nat Metab. 2020 Nov;2(11):1350-1367. doi: 10.1038/s42255-020-00306-2. Epub 2020 Nov 9. Nat Metab. 2020. PMID: 33168981 Free PMC article.
36 results