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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1964 1
1997 1
2007 1
2009 1
2011 1
2012 2
2013 1
2014 2
2015 4
2016 2
2017 1
2018 4
2020 3
2021 4
2024 0

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27 results

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Page 1
Scaling Concepts in Serpin Polymer Physics.
Raccosta S, Librizzi F, Jagger AM, Noto R, Martorana V, Lomas DA, Irving JA, Manno M. Raccosta S, et al. Among authors: jagger am. Materials (Basel). 2021 May 15;14(10):2577. doi: 10.3390/ma14102577. Materials (Basel). 2021. PMID: 34063488 Free PMC article.
The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding.
Liddle J, Pearce AC, Arico-Muendel C, Belyanskaya S, Brewster A, Brown M, Chung CW, Denis A, Dodic N, Dossang A, Eddershaw P, Klimaszewska D, Haq I, Holmes DS, Jagger A, Jakhria T, Jigorel E, Lind K, Messer J, Neu M, Olszewski A, Ronzoni R, Rowedder J, Rüdiger M, Skinner S, Smith KJ, Trottet L, Uings I, Zhu Z, Irving JA, Lomas DA. Liddle J, et al. Among authors: jagger a. Bioorg Med Chem Lett. 2021 Jun 1;41:127973. doi: 10.1016/j.bmcl.2021.127973. Epub 2021 Mar 19. Bioorg Med Chem Lett. 2021. PMID: 33753261
Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin.
Lomas DA, Irving JA, Arico-Muendel C, Belyanskaya S, Brewster A, Brown M, Chung CW, Dave H, Denis A, Dodic N, Dossang A, Eddershaw P, Klimaszewska D, Haq I, Holmes DS, Hutchinson JP, Jagger AM, Jakhria T, Jigorel E, Liddle J, Lind K, Marciniak SJ, Messer J, Neu M, Olszewski A, Ordonez A, Ronzoni R, Rowedder J, Rüdiger M, Skinner S, Smith KJ, Terry R, Trottet L, Uings I, Wilson S, Zhu Z, Pearce AC. Lomas DA, et al. Among authors: jagger am. EMBO Mol Med. 2021 Mar 5;13(3):e13167. doi: 10.15252/emmm.202013167. Epub 2021 Jan 29. EMBO Mol Med. 2021. PMID: 33512066 Free PMC article.
The structural basis for Z α1-antitrypsin polymerization in the liver.
Faull SV, Elliston ELK, Gooptu B, Jagger AM, Aldobiyan I, Redzej A, Badaoui M, Heyer-Chauhan N, Rashid ST, Reynolds GM, Adams DH, Miranda E, Orlova EV, Irving JA, Lomas DA. Faull SV, et al. Among authors: jagger am. Sci Adv. 2020 Oct 21;6(43):eabc1370. doi: 10.1126/sciadv.abc1370. Print 2020 Oct. Sci Adv. 2020. PMID: 33087346 Free PMC article.
Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin.
Laffranchi M, Elliston EL, Miranda E, Perez J, Ronzoni R, Jagger AM, Heyer-Chauhan N, Brantly ML, Fra A, Lomas DA, Irving JA. Laffranchi M, et al. Among authors: jagger am. JCI Insight. 2020 Jul 23;5(14):e135459. doi: 10.1172/jci.insight.135459. JCI Insight. 2020. PMID: 32699193 Free PMC article.
Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm.
Adam M, Kooreman NG, Jagger A, Wagenhäuser MU, Mehrkens D, Wang Y, Kayama Y, Toyama K, Raaz U, Schellinger IN, Maegdefessel L, Spin JM, Hamming JF, Quax PHA, Baldus S, Wu JC, Tsao PS. Adam M, et al. Among authors: jagger a. Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1796-1805. doi: 10.1161/ATVBAHA.117.310672. Arterioscler Thromb Vasc Biol. 2018. PMID: 29880489 Free PMC article.
MicroRNA-Mediated Therapy Modulating Blood-Brain Barrier Disruption Improves Vascular Cognitive Impairment.
Toyama K, Spin JM, Deng AC, Huang TT, Wei K, Wagenhäuser MU, Yoshino T, Nguyen H, Mulorz J, Kundu S, Raaz U, Adam M, Schellinger IN, Jagger A, Tsao PS. Toyama K, et al. Among authors: jagger a. Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):1392-1406. doi: 10.1161/ATVBAHA.118.310822. Epub 2018 Apr 12. Arterioscler Thromb Vasc Biol. 2018. PMID: 29650692
27 results