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Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin A.
Botas A, Eitel M, Schwarz PN, Buchmann A, Costales P, Núñez LE, Cortés J, Morís F, Krawiec M, Wolański M, Gust B, Rodriguez M, Fischer WN, Jandeleit B, Zakrzewska-Czerwińska J, Wohlleben W, Stegmann E, Koch P, Méndez C, Gross H. Botas A, et al. Among authors: jandeleit b. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13536-13541. doi: 10.1002/anie.202015852. Epub 2021 May 1. Angew Chem Int Ed Engl. 2021. PMID: 33768597 Free PMC article.
A Novel Brain-Permeant Chemotherapeutic Agent for the Treatment of Brain Metastasis in Triple-Negative Breast Cancer.
Deng J, Chernikova SB, Wang Y, Rodriguez ML, Andersen SJ, Umeh-Garcia MC, Godfrey BO, Ahmadian SS, Fischer WN, Koller KJ, Jandeleit B, Ringold GM, Gephart MH. Deng J, et al. Among authors: jandeleit b. Mol Cancer Ther. 2021 Nov;20(11):2110-2116. doi: 10.1158/1535-7163.MCT-21-0140. Epub 2021 Oct 11. Mol Cancer Ther. 2021. PMID: 34635566 Free PMC article.
Successful anti-tumor effects with two novel bifunctional chemotherapeutic compounds that combine a LAT1 substrate with cytotoxic moieties in aggressive T-cell lymphomas.
Murga-Zamalloa C, Webb S, Reneau J, Zevallos A, Danos-Diaz P, Perez-Silos V, Rodriguez M, Gao G, Fischer WN, Jandeleit B, Wilcox R. Murga-Zamalloa C, et al. Among authors: jandeleit b. Leuk Res Rep. 2023 Nov 22;21:100398. doi: 10.1016/j.lrr.2023.100398. eCollection 2024. Leuk Res Rep. 2023. PMID: 38192502 Free PMC article.
Acamprosate produces its anti-relapse effects via calcium.
Spanagel R, Vengeliene V, Jandeleit B, Fischer WN, Grindstaff K, Zhang X, Gallop MA, Krstew EV, Lawrence AJ, Kiefer F. Spanagel R, et al. Among authors: jandeleit b. Neuropsychopharmacology. 2014 Mar;39(4):783-91. doi: 10.1038/npp.2013.264. Epub 2013 Sep 30. Neuropsychopharmacology. 2014. PMID: 24081303 Free PMC article.
Combinatorial Materials Science and Catalysis.
Jandeleit B, Schaefer DJ, Powers TS, Turner HW, Weinberg WH. Jandeleit B, et al. Angew Chem Int Ed Engl. 1999 Sep;38(17):2494-2532. Angew Chem Int Ed Engl. 1999. PMID: 10508328