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342 results

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Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.
Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL, Zhang J, Orth AP, Walker JR, Glynne RJ, Cooke MP, Takahashi JS, Shimomura K, Kohsaka A, Bass J, Saez E, Wiltshire T, Su AI. Wu C, et al. Among authors: janes j. PLoS Genet. 2008 May 9;4(5):e1000070. doi: 10.1371/journal.pgen.1000070. PLoS Genet. 2008. PMID: 18464898 Free PMC article.
A genome-wide RNAi screen for modifiers of the circadian clock in human cells.
Zhang EE, Liu AC, Hirota T, Miraglia LJ, Welch G, Pongsawakul PY, Liu X, Atwood A, Huss JW 3rd, Janes J, Su AI, Hogenesch JB, Kay SA. Zhang EE, et al. Among authors: janes j. Cell. 2009 Oct 2;139(1):199-210. doi: 10.1016/j.cell.2009.08.031. Epub 2009 Sep 17. Cell. 2009. PMID: 19765810 Free PMC article.
An efficient rapid system for profiling the cellular activities of molecular libraries.
Melnick JS, Janes J, Kim S, Chang JY, Sipes DG, Gunderson D, Jarnes L, Matzen JT, Garcia ME, Hood TL, Beigi R, Xia G, Harig RA, Asatryan H, Yan SF, Zhou Y, Gu XJ, Saadat A, Zhou V, King FJ, Shaw CM, Su AI, Downs R, Gray NS, Schultz PG, Warmuth M, Caldwell JS. Melnick JS, et al. Among authors: janes j. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3153-8. doi: 10.1073/pnas.0511292103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492761 Free PMC article.
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.
Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, Slepian PM, Clarke S, Drenan RM, Janes J, Al Sharari S, Segall SK, Aasvang EK, Lai W, Bittner R, Richards CI, Slade GD, Kehlet H, Walker J, Maskos U, Changeux JP, Devor M, Maixner W, Diatchenko L, Belfer I, Dougherty DA, Su AI, Lummis SC, Imad Damaj M, Lester HA, Patapoutian A, Mogil JS. Wieskopf JS, et al. Among authors: janes j. Sci Transl Med. 2015 May 13;7(287):287ra72. doi: 10.1126/scitranslmed.3009986. Sci Transl Med. 2015. PMID: 25972004 Free PMC article.
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.
Janes J, Young ME, Chen E, Rogers NH, Burgstaller-Muehlbacher S, Hughes LD, Love MS, Hull MV, Kuhen KL, Woods AK, Joseph SB, Petrassi HM, McNamara CW, Tremblay MS, Su AI, Schultz PG, Chatterjee AK. Janes J, et al. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10750-10755. doi: 10.1073/pnas.1810137115. Epub 2018 Oct 3. Proc Natl Acad Sci U S A. 2018. PMID: 30282735 Free PMC article.
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Plouffe D, Brinker A, McNamara C, Henson K, Kato N, Kuhen K, Nagle A, Adrián F, Matzen JT, Anderson P, Nam TG, Gray NS, Chatterjee A, Janes J, Yan SF, Trager R, Caldwell JS, Schultz PG, Zhou Y, Winzeler EA. Plouffe D, et al. Among authors: janes j. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9059-64. doi: 10.1073/pnas.0802982105. Epub 2008 Jun 25. Proc Natl Acad Sci U S A. 2008. PMID: 18579783 Free PMC article.
Development of a genetic selection for catalytic antibodies.
Gildersleeve J, Janes J, Ulrich H, Yang P, Barbas C, Schultz PG. Gildersleeve J, et al. Among authors: janes j. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1691-4. doi: 10.1016/s0960-894x(02)00198-1. Bioorg Med Chem Lett. 2002. PMID: 12039592
342 results