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Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood.
Treviño LS, Dong J, Kaushal A, Katz TA, Jangid RK, Robertson MJ, Grimm SL, Ambati CSR, Putluri V, Cox AR, Kim KH, May TD, Gallo MR, Moore DD, Hartig SM, Foulds CE, Putluri N, Coarfa C, Walker CL. Treviño LS, et al. Among authors: jangid rk. Nat Commun. 2020 May 8;11(1):2316. doi: 10.1038/s41467-020-15847-z. Nat Commun. 2020. PMID: 32385268 Free PMC article.
Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin.
Katz TA, Grimm SL, Kaushal A, Dong J, Treviño LS, Jangid RK, Gaitán AV, Bertocchio JP, Guan Y, Robertson MJ, Cabrera RM, Finegold MJ, Foulds CE, Coarfa C, Walker CL. Katz TA, et al. Among authors: jangid rk. Environ Health Perspect. 2020 Jan;128(1):17010. doi: 10.1289/EHP5414. Epub 2020 Jan 15. Environ Health Perspect. 2020. PMID: 31939706 Free PMC article.
An actin-WHAMM interaction linking SETD2 and autophagy.
Seervai RNH, Grimm SL, Jangid RK, Tripathi DN, Coarfa C, Walker CL. Seervai RNH, et al. Among authors: jangid rk. Biochem Biophys Res Commun. 2021 Jun 18;558:202-208. doi: 10.1016/j.bbrc.2020.09.025. Epub 2020 Oct 6. Biochem Biophys Res Commun. 2021. PMID: 33036756 Free PMC article.
Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice.
Koenning M, Wang X, Karki M, Jangid RK, Kearns S, Tripathi DN, Cianfrocco M, Verhey KJ, Jung SY, Coarfa C, Ward CS, Kalish BT, Grimm SL, Rathmell WK, Mostany R, Dere R, Rasband MN, Walker CL, Park IY. Koenning M, et al. Among authors: jangid rk. Brain. 2021 Sep 4;144(8):2527-2540. doi: 10.1093/brain/awab200. Brain. 2021. PMID: 34014281 Free PMC article.
A cytoskeletal function for PBRM1 reading methylated microtubules.
Karki M, Jangid RK, Anish R, Seervai RNH, Bertocchio JP, Hotta T, Msaouel P, Jung SY, Grimm SL, Coarfa C, Weissman BE, Ohi R, Verhey KJ, Hodges HC, Burggren W, Dere R, Park IY, Prasad BVV, Rathmell WK, Walker CL, Tripathi DN. Karki M, et al. Among authors: jangid rk. Sci Adv. 2021 Apr 2;7(14):eabf2866. doi: 10.1126/sciadv.abf2866. Print 2021 Apr. Sci Adv. 2021. PMID: 33811077 Free article.
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL. Seervai RNH, et al. Among authors: jangid rk. Sci Adv. 2020 Oct 2;6(40):eabb7854. doi: 10.1126/sciadv.abb7854. Print 2020 Oct. Sci Adv. 2020. PMID: 33008892 Free PMC article.
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