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Page 1
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance.
Liu Y, Jurczak MJ, Lear TB, Lin B, Larsen MB, Kennerdell JR, Chen Y, Huckestein BR, Nguyen MK, Tuncer F, Jiang Y, Monga SP, O'Donnell CP, Finkel T, Chen BB, Mallampalli RK. Liu Y, et al. Among authors: kennerdell jr. Nat Chem Biol. 2021 Mar;17(3):298-306. doi: 10.1038/s41589-020-00723-0. Epub 2021 Jan 25. Nat Chem Biol. 2021. PMID: 33495648 Free PMC article.
Modulation of lysosomal function as a therapeutic approach for coronaviral infections.
Liu Y, Lear T, Larsen M, Lin B, Cao Q, Alfaras I, Kennerdell J, Salminen L, Camarco D, Lockwood K, Ma J, Liu J, Tan J, Myerburg M, Chen Y, St Croix C, Sekine Y, Evankovich J, Finkel T, Chen B. Liu Y, et al. Among authors: kennerdell j. Res Sq [Preprint]. 2021 Apr 23:rs.3.rs-419305. doi: 10.21203/rs.3.rs-419305/v1. Res Sq. 2021. PMID: 34013250 Free PMC article. Preprint.
A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry.
Chen Y, Lear TB, Evankovich JW, Larsen MB, Lin B, Alfaras I, Kennerdell JR, Salminen L, Camarco DP, Lockwood KC, Tuncer F, Liu J, Myerburg MM, McDyer JF, Liu Y, Finkel T, Chen BB. Chen Y, et al. Among authors: kennerdell jr. Nat Commun. 2021 Jun 23;12(1):3907. doi: 10.1038/s41467-021-24156-y. Nat Commun. 2021. PMID: 34162861 Free PMC article.
Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.
Lear TB, Lockwood KC, Larsen M, Tuncer F, Kennerdell JR, Morse C, Valenzi E, Tabib T, Jurczak MJ, Kass DJ, Evankovich JW, Finkel T, Lafyatis R, Liu Y, Chen BB. Lear TB, et al. Among authors: kennerdell jr. J Biol Chem. 2020 Mar 27;295(13):4171-4180. doi: 10.1074/jbc.AC119.012066. Epub 2020 Feb 17. J Biol Chem. 2020. PMID: 32071084 Free PMC article.
A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry.
Chen Y, Lear TB, Evankovich JW, Larsen MB, Lin B, Alfaras I, Kennerdell JR, Salminen L, Camarco DP, Lockwood KC, Liu J, Myerburg MM, McDyer JF, Liu Y, Finkel T, Chen BB. Chen Y, et al. Among authors: kennerdell jr. Res Sq [Preprint]. 2020 Aug 14:rs.3.rs-48659. doi: 10.21203/rs.3.rs-48659/v1. Res Sq. 2020. PMID: 32818215 Free PMC article. Updated. Preprint.
12 results