Jayasena SD - Search Results

1

Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity.

Khvorova A, Lescoute A, Westhof E, Jayasena SD. Khvorova A, et al. Among authors: jayasena sd. Nat Struct Biol. 2003 Sep;10(9):708-12. doi: 10.1038/nsb959. Epub 2003 Jul 27. Nat Struct Biol. 2003. PMID: 12881719

2

Functional siRNAs and miRNAs exhibit strand bias.

Khvorova A, Reynolds A, Jayasena SD. Khvorova A, et al. Among authors: jayasena sd. Cell. 2003 Oct 17;115(2):209-16. doi: 10.1016/s0092-8674(03)00801-8. Cell. 2003. PMID: 14567918 Free article.

3

Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements.

Penedo JC, Wilson TJ, Jayasena SD, Khvorova A, Lilley DM. Penedo JC, et al. Among authors: jayasena sd. RNA. 2004 May;10(5):880-8. doi: 10.1261/rna.5268404. RNA. 2004. PMID: 15100442 Free PMC article.

4

Fast cleavage kinetics of a natural hammerhead ribozyme.

Canny MD, Jucker FM, Kellogg E, Khvorova A, Jayasena SD, Pardi A. Canny MD, et al. Among authors: jayasena sd. J Am Chem Soc. 2004 Sep 8;126(35):10848-9. doi: 10.1021/ja046848v. J Am Chem Soc. 2004. PMID: 15339162

5

Artificial tertiary motifs stabilize trans-cleaving hammerhead ribozymes under conditions of submillimolar divalent ions and high temperatures.

Saksmerprome V, Roychowdhury-Saha M, Jayasena S, Khvorova A, Burke DH. Saksmerprome V, et al. RNA. 2004 Dec;10(12):1916-24. doi: 10.1261/rna.7159504. RNA. 2004. PMID: 15547137 Free PMC article.

6

RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells.

Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG, Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. Wilson JA, et al. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2783-8. doi: 10.1073/pnas.252758799. Epub 2003 Feb 19. Proc Natl Acad Sci U S A. 2003. PMID: 12594341 Free PMC article.

7

Site-specific cleavage of the transactivation response site of human immunodeficiency virus RNA with a tat-based chemical nuclease.

Jayasena SD, Johnston BH. Jayasena SD, et al. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3526-30. doi: 10.1073/pnas.89.8.3526. Proc Natl Acad Sci U S A. 1992. PMID: 1565648 Free PMC article.

8

Modified RNA sequence pools for in vitro selection.

Lin Y, Qiu Q, Gill SC, Jayasena SD. Lin Y, et al. Among authors: jayasena sd. Nucleic Acids Res. 1994 Dec 11;22(24):5229-34. doi: 10.1093/nar/22.24.5229. Nucleic Acids Res. 1994. PMID: 7529404 Free PMC article.

9

Oligonucleotide-directed triple helix formation at adjacent oligopurine and oligopyrimidine DNA tracts by alternate strand recognition.

Jayasena SD, Johnston BH. Jayasena SD, et al. Nucleic Acids Res. 1992 Oct 25;20(20):5279-88. doi: 10.1093/nar/20.20.5279. Nucleic Acids Res. 1992. PMID: 1437547 Free PMC article.

10

Intramolecular triple-helix formation at (PunPyn).(PunPyn) tracts: recognition of alternate strands via Pu.PuPy and Py.PuPy base triplets.

Jayasena SD, Johnston BH. Jayasena SD, et al. Biochemistry. 1992 Jan 21;31(2):320-7. doi: 10.1021/bi00117a002. Biochemistry. 1992. PMID: 1731890

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