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Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment.
Sommerfeld L, Knuth I, Finkernagel F, Pesek J, Nockher WA, Jansen JM, Wagner U, Nist A, Stiewe T, Müller-Brüsselbach S, Müller R, Reinartz S. Sommerfeld L, et al. Among authors: pesek j. Cancers (Basel). 2022 Dec 13;14(24):6154. doi: 10.3390/cancers14246154. Cancers (Basel). 2022. PMID: 36551640 Free PMC article.
Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK-STAT signaling in macrophages by perturbing lipid raft structures.
Hammoud MK, Dietze R, Pesek J, Finkernagel F, Unger A, Bieringer T, Nist A, Stiewe T, Bhagwat AM, Nockher WA, Reinartz S, Müller-Brüsselbach S, Graumann J, Müller R. Hammoud MK, et al. Among authors: pesek j. Mol Oncol. 2022 Sep;16(17):3146-3166. doi: 10.1002/1878-0261.13221. Epub 2022 May 4. Mol Oncol. 2022. PMID: 35451191 Free PMC article.
Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment.
Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R. Reinartz S, et al. Among authors: pesek j. Mol Oncol. 2019 Feb;13(2):185-201. doi: 10.1002/1878-0261.12396. Epub 2018 Nov 15. Mol Oncol. 2019. PMID: 30353652 Free PMC article.
A Novel Approach for Glioblastoma Treatment by Combining Apoptosis Inducers (TMZ, MTX, and Cytarabine) with E.V.A. (Eltanexor, Venetoclax, and A1210477) Inhibiting XPO1, Bcl-2, and Mcl-1.
Zhao K, Braun M, Meyer L, Otte K, Raifer H, Helmprobst F, Möschl V, Pagenstecher A, Urban H, Ronellenfitsch MW, Steinbach JP, Pesek J, Watzer B, Nockher WA, Taudte RV, Neubauer A, Nimsky C, Bartsch JW, Rusch T. Zhao K, et al. Among authors: pesek j. Cells. 2024 Apr 4;13(7):632. doi: 10.3390/cells13070632. Cells. 2024. PMID: 38607071 Free PMC article.