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MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.
Leukemia. 2021 Dec;35(12):3394-3405. doi: 10.1038/s41375-021-01291-5. Epub 2021 May 18.
Leukemia. 2021.
PMID: 34007050
Free article.
Comparative kinase and cancer cell panel profiling of kinase inhibitors approved for clinical use from 2018 to 2020.
Kooijman JJ, van Riel WE, Dylus J, Prinsen MBW, Grobben Y, de Bitter TJJ, van Doornmalen AM, Melis JJTM, Uitdehaag JCM, Narumi Y, Kawase Y, de Roos JADM, Willemsen-Seegers N, Zaman GJR.
Kooijman JJ, et al. Among authors: dylus j.
Front Oncol. 2022 Sep 14;12:953013. doi: 10.3389/fonc.2022.953013. eCollection 2022.
Front Oncol. 2022.
PMID: 36185300
Free PMC article.
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Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites.
den Ouden JE, Zaman GJR, Dylus J, van Doornmalen AM, Mulder WR, Grobben Y, van Riel WE, de Hullu JA, Buijsman RC, van Altena AM.
den Ouden JE, et al. Among authors: dylus j.
Oncotarget. 2020 Dec 8;11(49):4570-4581. doi: 10.18632/oncotarget.27827. eCollection 2020 Dec 8.
Oncotarget. 2020.
PMID: 33346216
Free PMC article.
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Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines.
Libouban MAA, de Roos JADM, Uitdehaag JCM, Willemsen-Seegers N, Mainardi S, Dylus J, de Man J, Tops B, Meijerink JPP, Storchová Z, Buijsman RC, Medema RH, Zaman GJR.
Libouban MAA, et al. Among authors: dylus j.
Oncotarget. 2017 Jun 13;8(24):38309-38325. doi: 10.18632/oncotarget.16213.
Oncotarget. 2017.
PMID: 28415765
Free PMC article.
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Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017.
Uitdehaag JCM, Kooijman JJ, de Roos JADM, Prinsen MBW, Dylus J, Willemsen-Seegers N, Kawase Y, Sawa M, de Man J, van Gerwen SJC, Buijsman RC, Zaman GJR.
Uitdehaag JCM, et al. Among authors: dylus j.
Mol Cancer Ther. 2019 Feb;18(2):470-481. doi: 10.1158/1535-7163.MCT-18-0877. Epub 2018 Oct 31.
Mol Cancer Ther. 2019.
PMID: 30381447
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Cell Panel Profiling Reveals Conserved Therapeutic Clusters and Differentiates the Mechanism of Action of Different PI3K/mTOR, Aurora Kinase and EZH2 Inhibitors.
Uitdehaag JC, de Roos JA, Prinsen MB, Willemsen-Seegers N, de Vetter JR, Dylus J, van Doornmalen AM, Kooijman J, Sawa M, van Gerwen SJ, de Man J, Buijsman RC, Zaman GJ.
Uitdehaag JC, et al. Among authors: dylus j.
Mol Cancer Ther. 2016 Dec;15(12):3097-3109. doi: 10.1158/1535-7163.MCT-16-0403. Epub 2016 Sep 1.
Mol Cancer Ther. 2016.
PMID: 27587489
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