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Page 1
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus.
Wu Z, Berlemann LA, Bader V, Sehr DA, Dawin E, Covallero A, Meschede J, Angersbach L, Showkat C, Michaelis JB, Münch C, Rieger B, Namgaladze D, Herrera MG, Fiesel FC, Springer W, Mendes M, Stepien J, Barkovits K, Marcus K, Sickmann A, Dittmar G, Busch KB, Riedel D, Brini M, Tatzelt J, Cali T, Winklhofer KF. Wu Z, et al. Among authors: meschede j. EMBO J. 2022 Dec 15;41(24):e112006. doi: 10.15252/embj.2022112006. Epub 2022 Nov 18. EMBO J. 2022. PMID: 36398858 Free PMC article.
A protein quality control pathway regulated by linear ubiquitination.
van Well EM, Bader V, Patra M, Sánchez-Vicente A, Meschede J, Furthmann N, Schnack C, Blusch A, Longworth J, Petrasch-Parwez E, Mori K, Arzberger T, Trümbach D, Angersbach L, Showkat C, Sehr DA, Berlemann LA, Goldmann P, Clement AM, Behl C, Woerner AC, Saft C, Wurst W, Haass C, Ellrichmann G, Gold R, Dittmar G, Hipp MS, Hartl FU, Tatzelt J, Winklhofer KF. van Well EM, et al. Among authors: meschede j. EMBO J. 2019 May 2;38(9):e100730. doi: 10.15252/embj.2018100730. Epub 2019 Mar 18. EMBO J. 2019. PMID: 30886048 Free PMC article.
The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC.
Meschede J, Šadić M, Furthmann N, Miedema T, Sehr DA, Müller-Rischart AK, Bader V, Berlemann LA, Pilsl A, Schlierf A, Barkovits K, Kachholz B, Rittinger K, Ikeda F, Marcus K, Schaefer L, Tatzelt J, Winklhofer KF. Meschede J, et al. Sci Signal. 2020 Feb 4;13(617):eaav1256. doi: 10.1126/scisignal.aav1256. Sci Signal. 2020. PMID: 32019898 Free PMC article.