Jensen JP - Search Results

1

Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells.

Yang Y, Ludwig RL, Jensen JP, Pierre SA, Medaglia MV, Davydov IV, Safiran YJ, Oberoi P, Kenten JH, Phillips AC, Weissman AM, Vousden KH. Yang Y, et al. Among authors: jensen jp. Cancer Cell. 2005 Jun;7(6):547-59. doi: 10.1016/j.ccr.2005.04.029. Cancer Cell. 2005. PMID: 15950904 Free article.

2

Expression and evaluation of RING finger proteins.

Yang Y, Lorick KL, Jensen JP, Weissman AM. Yang Y, et al. Among authors: jensen jp. Methods Enzymol. 2005;398:103-12. doi: 10.1016/S0076-6879(05)98010-5. Methods Enzymol. 2005. PMID: 16275323

3

Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics.

Yang Y, Kitagaki J, Dai RM, Tsai YC, Lorick KL, Ludwig RL, Pierre SA, Jensen JP, Davydov IV, Oberoi P, Li CC, Kenten JH, Beutler JA, Vousden KH, Weissman AM. Yang Y, et al. Among authors: jensen jp. Cancer Res. 2007 Oct 1;67(19):9472-81. doi: 10.1158/0008-5472.CAN-07-0568. Cancer Res. 2007. PMID: 17909057

4

Assay for ubiquitin ligase activity: high-throughput screen for inhibitors of HDM2.

Davydov IV, Woods D, Safiran YJ, Oberoi P, Fearnhead HO, Fang S, Jensen JP, Weissman AM, Kenten JH, Vousden KH. Davydov IV, et al. Among authors: jensen jp. J Biomol Screen. 2004 Dec;9(8):695-703. doi: 10.1177/1087057104267956. J Biomol Screen. 2004. PMID: 15634796

5

RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer.

Fang S, Lorick KL, Jensen JP, Weissman AM. Fang S, et al. Among authors: jensen jp. Semin Cancer Biol. 2003 Feb;13(1):5-14. doi: 10.1016/s1044-579x(02)00095-0. Semin Cancer Biol. 2003. PMID: 12507552 Review.

6

Expression, purification, and properties of the Ubc4/5 family of E2 enzymes.

Lorick KL, Jensen JP, Weissman AM. Lorick KL, et al. Among authors: jensen jp. Methods Enzymol. 2005;398:54-68. doi: 10.1016/S0076-6879(05)98006-3. Methods Enzymol. 2005. PMID: 16275319

7

Studies of the ubiquitin proteasome system.

Lorick KL, Yang Y, Jensen JP, Iwai K, Weissman AM. Lorick KL, et al. Among authors: jensen jp. Curr Protoc Cell Biol. 2006 Jul;Chapter 15:Unit 15.9. doi: 10.1002/0471143030.cb1509s31. Curr Protoc Cell Biol. 2006. PMID: 18228479

8

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53.

Fang S, Jensen JP, Ludwig RL, Vousden KH, Weissman AM. Fang S, et al. Among authors: jensen jp. J Biol Chem. 2000 Mar 24;275(12):8945-51. doi: 10.1074/jbc.275.12.8945. J Biol Chem. 2000. PMID: 10722742 Free article.

9

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli.

Yang Y, Fang S, Jensen JP, Weissman AM, Ashwell JD. Yang Y, et al. Among authors: jensen jp. Science. 2000 May 5;288(5467):874-7. doi: 10.1126/science.288.5467.874. Science. 2000. PMID: 10797013

10

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum.

Fang S, Ferrone M, Yang C, Jensen JP, Tiwari S, Weissman AM. Fang S, et al. Among authors: jensen jp. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14422-7. doi: 10.1073/pnas.251401598. Epub 2001 Nov 27. Proc Natl Acad Sci U S A. 2001. PMID: 11724934 Free PMC article.

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