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Year | Number of Results |
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2020 | 3 |
2021 | 4 |
2024 | 0 |
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Page 1
Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy.
Signal Transduct Target Ther. 2021 Aug 30;6(1):323. doi: 10.1038/s41392-021-00728-8.
Signal Transduct Target Ther. 2021.
PMID: 34462428
Free PMC article.
Review.
Harnessing the Nucleolar DNA Damage Response in Cancer Therapy.
Xuan J, Gitareja K, Brajanovski N, Sanij E.
Xuan J, et al.
Genes (Basel). 2021 Jul 28;12(8):1156. doi: 10.3390/genes12081156.
Genes (Basel). 2021.
PMID: 34440328
Free PMC article.
Review.
Item in Clipboard
The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function.
Koltowska K, Okuda KS, Gloger M, Rondon-Galeano M, Mason E, Xuan J, Dudczig S, Chen H, Arnold H, Skoczylas R, Bower NI, Paterson S, Lagendijk AK, Baillie GJ, Leshchiner I, Simons C, Smith KA, Goessling W, Heath JK, Pearson RB, Sanij E, Schulte-Merker S, Hogan BM.
Koltowska K, et al. Among authors: xuan j.
Nat Cell Biol. 2021 Nov;23(11):1136-1147. doi: 10.1038/s41556-021-00784-w. Epub 2021 Nov 8.
Nat Cell Biol. 2021.
PMID: 34750583
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CX-5461 can destabilize replication forks in PARP inhibitor-resistant models of ovarian cancer.
Xuan J, Pearson RB, Sanij E.
Xuan J, et al.
Mol Cell Oncol. 2020 Aug 31;7(6):1805256. doi: 10.1080/23723556.2020.1805256.
Mol Cell Oncol. 2020.
PMID: 33235908
Free PMC article.
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CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer.
Sanij E, Hannan KM, Xuan J, Yan S, Ahern JE, Trigos AS, Brajanovski N, Son J, Chan KT, Kondrashova O, Lieschke E, Wakefield MJ, Frank D, Ellis S, Cullinane C, Kang J, Poortinga G, Nag P, Deans AJ, Khanna KK, Mileshkin L, McArthur GA, Soong J, Berns EMJJ, Hannan RD, Scott CL, Sheppard KE, Pearson RB.
Sanij E, et al. Among authors: xuan j.
Nat Commun. 2020 May 26;11(1):2641. doi: 10.1038/s41467-020-16393-4.
Nat Commun. 2020.
PMID: 32457376
Free PMC article.
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The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.
Yan S, Xuan J, Brajanovski N, Tancock MRC, Madhamshettiwar PB, Simpson KJ, Ellis S, Kang J, Cullinane C, Sheppard KE, Hannan KM, Hannan RD, Sanij E, Pearson RB, Chan KT.
Yan S, et al. Among authors: xuan j.
Br J Cancer. 2021 Feb;124(3):616-627. doi: 10.1038/s41416-020-01158-z. Epub 2020 Nov 11.
Br J Cancer. 2021.
PMID: 33173151
Free PMC article.
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