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Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation.
Chen Z, Cui Y, Yao Y, Liu B, Yunis J, Gao X, Wang N, Cañete PF, Tuong ZK, Sun H, Wang H, Yang S, Wang R, Leong YA, Simon Davis D, Qin J, Liang K, Deng J, Wang CK, Huang YH, Roco JA, Nettelfield S, Zhu H, Xu H, Yu Z, Craik D, Liu Z, Qi H, Parish C, Yu D. Chen Z, et al. Among authors: qin j. Sci Immunol. 2023 Feb 24;8(80):eadd1728. doi: 10.1126/sciimmunol.add1728. Epub 2023 Feb 17. Sci Immunol. 2023. PMID: 36800411