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Did you mean jianmin ruan[Author] (3 results)?
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, Kim J, Lieberman J, Wu H. Hu JJ, et al. Among authors: ruan j. Nat Immunol. 2020 Jul;21(7):736-745. doi: 10.1038/s41590-020-0669-6. Epub 2020 May 4. Nat Immunol. 2020. PMID: 32367036 Free PMC article.
Inflammasomes.
Ruan J. Ruan J. Mol Aspects Med. 2020 Dec;76:100934. doi: 10.1016/j.mam.2020.100934. Epub 2020 Nov 18. Mol Aspects Med. 2020. PMID: 33218678 No abstract available.
Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors.
Xiong X, Tian S, Yang P, Lebreton F, Bao H, Sheng K, Yin L, Chen P, Zhang J, Qi W, Ruan J, Wu H, Chen H, Breault DT, Wu H, Earl AM, Gilmore MS, Abraham J, Dong M. Xiong X, et al. Among authors: ruan j. Cell. 2022 Mar 31;185(7):1157-1171.e22. doi: 10.1016/j.cell.2022.02.002. Epub 2022 Mar 7. Cell. 2022. PMID: 35259335 Free PMC article.
Structural basis for GSDMB pore formation and its targeting by IpaH7.8.
Wang C, Shivcharan S, Tian T, Wright S, Ma D, Chang J, Li K, Song K, Xu C, Rathinam VA, Ruan J. Wang C, et al. Among authors: ruan j. Nature. 2023 Apr;616(7957):590-597. doi: 10.1038/s41586-023-05832-z. Epub 2023 Mar 29. Nature. 2023. PMID: 36991122 Free PMC article.
Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Xia S, et al. Among authors: ruan j. Nature. 2021 May;593(7860):607-611. doi: 10.1038/s41586-021-03478-3. Epub 2021 Apr 21. Nature. 2021. PMID: 33883744 Free PMC article.
NLRP inflammasomes in health and disease.
Xu Z, Kombe Kombe AJ, Deng S, Zhang H, Wu S, Ruan J, Zhou Y, Jin T. Xu Z, et al. Among authors: ruan j. Mol Biomed. 2024 Apr 22;5(1):14. doi: 10.1186/s43556-024-00179-x. Mol Biomed. 2024. PMID: 38644450 Free PMC article. Review.
Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin.
Russo AJ, Vasudevan SO, Méndez-Huergo SP, Kumari P, Menoret A, Duduskar S, Wang C, Pérez Sáez JM, Fettis MM, Li C, Liu R, Wanchoo A, Chandiran K, Ruan J, Vanaja SK, Bauer M, Sponholz C, Hudalla GA, Vella AT, Zhou B, Deshmukh SD, Rabinovich GA, Rathinam VA. Russo AJ, et al. Among authors: ruan j. Nat Immunol. 2021 Feb;22(2):154-165. doi: 10.1038/s41590-020-00844-7. Epub 2021 Jan 4. Nat Immunol. 2021. PMID: 33398185 Free PMC article.
38 results