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Targeting AML-associated FLT3 mutations with a type I kinase inhibitor.
Jones LM, Melgar K, Bolanos L, Hueneman K, Walker MM, Jiang JK, Wilson KM, Zhang X, Shen J, Jiang F, Sutter P, Wang A, Xu X, Tawa GJ, Hoyt SB, Wunderlich M, O'Brien E, Perentesis JP, Starczynowski DT, Thomas CJ. Jones LM, et al. Among authors: jiang jk, jiang f. J Clin Invest. 2020 Apr 1;130(4):2017-2023. doi: 10.1172/JCI127907. J Clin Invest. 2020. PMID: 32149729 Free PMC article.
Overcoming adaptive therapy resistance in AML by targeting immune response pathways.
Melgar K, Walker MM, Jones LM, Bolanos LC, Hueneman K, Wunderlich M, Jiang JK, Wilson KM, Zhang X, Sutter P, Wang A, Xu X, Choi K, Tawa G, Lorimer D, Abendroth J, O'Brien E, Hoyt SB, Berman E, Famulare CA, Mulloy JC, Levine RL, Perentesis JP, Thomas CJ, Starczynowski DT. Melgar K, et al. Among authors: jiang jk. Sci Transl Med. 2019 Sep 4;11(508):eaaw8828. doi: 10.1126/scitranslmed.aaw8828. Sci Transl Med. 2019. PMID: 31484791 Free PMC article.
Chiral kinase inhibitors.
Jiang JK, Shen M, Thomas CJ, Boxer MB. Jiang JK, et al. Curr Top Med Chem. 2011;11(7):800-9. doi: 10.2174/156802611795165052. Curr Top Med Chem. 2011. PMID: 21291394 Free PMC article. Review.
Selective targeting of ITK blocks multiple steps of HIV replication.
Readinger JA, Schiralli GM, Jiang JK, Thomas CJ, August A, Henderson AJ, Schwartzberg PL. Readinger JA, et al. Among authors: jiang jk. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6684-9. doi: 10.1073/pnas.0709659105. Epub 2008 Apr 28. Proc Natl Acad Sci U S A. 2008. PMID: 18443296 Free PMC article.
Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.
Bian Y, Teper Y, Mathews Griner LA, Aiken TJ, Shukla V, Guha R, Shinn P, Xin HW, Pflicke H, Powers AS, Li D, Jiang JK, Patel P, Rogers SA, Aubé J, Ferrer M, Thomas CJ, Rudloff U. Bian Y, et al. Among authors: jiang jk. Mol Cancer Ther. 2019 Nov;18(11):2097-2110. doi: 10.1158/1535-7163.MCT-18-1011. Epub 2019 Aug 8. Mol Cancer Ther. 2019. PMID: 31395684 Free PMC article.
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.
Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang Y, Xu W, Shaffer AL, Wright G, Xiao W, Powell J, Jiang JK, Thomas CJ, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Johnson NA, Rimsza LM, Campo E, Jaffe ES, Wilson WH, Delabie J, Smeland EB, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pierce SK, Staudt LM. Davis RE, et al. Among authors: jiang jk. Nature. 2010 Jan 7;463(7277):88-92. doi: 10.1038/nature08638. Nature. 2010. PMID: 20054396 Free PMC article.
326 results