Jinek M - Search Results

1

Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.

Niewoehner O, Jinek M, Doudna JA. Niewoehner O, et al. Among authors: jinek m. Nucleic Acids Res. 2014 Jan;42(2):1341-53. doi: 10.1093/nar/gkt922. Epub 2013 Oct 22. Nucleic Acids Res. 2014. PMID: 24150936 Free PMC article.

2

PAM-Flexible Genome Editing with an Engineered Chimeric Cas9.

Koseki S, Hong L, Yudistyra V, Stan T, Tysinger E, Silverstein R, Kramme C, Amrani N, Savic N, Pacesa M, Rodriguez T, Ponnapati M, Jacobson J, Church G, Truant R, Jinek M, Kleinstiver B, Sontheimer E, Chatterjee P. Koseki S, et al. Among authors: jinek m. Res Sq [Preprint]. 2023 Mar 7:rs.3.rs-2625838. doi: 10.21203/rs.3.rs-2625838/v1. Res Sq. 2023. PMID: 36945419 Free PMC article. Updated. Preprint.

3

Structural basis for the assembly of the type V CRISPR-associated transposon complex.

Schmitz M, Querques I, Oberli S, Chanez C, Jinek M. Schmitz M, et al. Among authors: jinek m. Cell. 2022 Dec 22;185(26):4999-5010.e17. doi: 10.1016/j.cell.2022.11.009. Epub 2022 Nov 25. Cell. 2022. PMID: 36435179 Free PMC article.

4

Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.

Schmidheini L, Mathis N, Marquart KF, Rothgangl T, Kissling L, Böck D, Chanez C, Wang JP, Jinek M, Schwank G. Schmidheini L, et al. Among authors: jinek m. Nat Chem Biol. 2024 Mar;20(3):333-343. doi: 10.1038/s41589-023-01427-x. Epub 2023 Sep 21. Nat Chem Biol. 2024. PMID: 37735239

5

Publisher Correction: R-loop formation and conformational activation mechanisms of Cas9.

Pacesa M, Loeff L, Querques I, Muckenfuss LM, Sawicka M, Jinek M. Pacesa M, et al. Among authors: jinek m. Nature. 2023 Nov;623(7987):E10. doi: 10.1038/s41586-023-06779-x. Nature. 2023. PMID: 37903882 Free PMC article. No abstract available.

6

PAM-flexible genome editing with an engineered chimeric Cas9.

Zhao L, Koseki SRT, Silverstein RA, Amrani N, Peng C, Kramme C, Savic N, Pacesa M, Rodríguez TC, Stan T, Tysinger E, Hong L, Yudistyra V, Ponnapati MR, Jacobson JM, Church GM, Jakimo N, Truant R, Jinek M, Kleinstiver BP, Sontheimer EJ, Chatterjee P. Zhao L, et al. Among authors: jinek m. Nat Commun. 2023 Oct 4;14(1):6175. doi: 10.1038/s41467-023-41829-y. Nat Commun. 2023. PMID: 37794046 Free PMC article.

7

A three-dimensional view of the molecular machinery of RNA interference.

Jinek M, Doudna JA. Jinek M, et al. Nature. 2009 Jan 22;457(7228):405-12. doi: 10.1038/nature07755. Nature. 2009. PMID: 19158786 Review.

8

Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense.

Wiedenheft B, Zhou K, Jinek M, Coyle SM, Ma W, Doudna JA. Wiedenheft B, et al. Among authors: jinek m. Structure. 2009 Jun 10;17(6):904-12. doi: 10.1016/j.str.2009.03.019. Structure. 2009. PMID: 19523907 Free article.

9

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu AB, Yates JR 3rd, Hannon GJ, Filipowicz W, Duchaine TF, Sonenberg N. Fabian MR, et al. Among authors: jinek m. Mol Cell. 2009 Sep 24;35(6):868-80. doi: 10.1016/j.molcel.2009.08.004. Epub 2009 Aug 27. Mol Cell. 2009. PMID: 19716330 Free PMC article.

10

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.

Jinek M, Fabian MR, Coyle SM, Sonenberg N, Doudna JA. Jinek M, et al. Nat Struct Mol Biol. 2010 Feb;17(2):238-40. doi: 10.1038/nsmb.1768. Epub 2010 Jan 24. Nat Struct Mol Biol. 2010. PMID: 20098421 Free PMC article.

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