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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 5
2003 6
2004 7
2005 8
2006 2
2007 5
2008 4
2009 3
2010 3
2011 4
2012 3
2013 3
2014 4
2015 2
2016 1
2017 5
2018 3
2019 3
2020 5
2021 1
2022 3
2023 3
2024 1

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80 results

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Page 1
A novel antibiotic class targeting the lipopolysaccharide transporter.
Zampaloni C, Mattei P, Bleicher K, Winther L, Thäte C, Bucher C, Adam JM, Alanine A, Amrein KE, Baidin V, Bieniossek C, Bissantz C, Boess F, Cantrill C, Clairfeuille T, Dey F, Di Giorgio P, du Castel P, Dylus D, Dzygiel P, Felici A, García-Alcalde F, Haldimann A, Leipner M, Leyn S, Louvel S, Misson P, Osterman A, Pahil K, Rigo S, Schäublin A, Scharf S, Schmitz P, Stoll T, Trauner A, Zoffmann S, Kahne D, Young JAT, Lobritz MA, Bradley KA. Zampaloni C, et al. Among authors: young jat. Nature. 2024 Jan;625(7995):566-571. doi: 10.1038/s41586-023-06873-0. Epub 2024 Jan 3. Nature. 2024. PMID: 38172634 Free PMC article.
Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus.
Kou B, Zhang Z, Han X, Zhou Z, Xu Z, Zhou X, Shen F, Zhou Y, Tian X, Yang G, Young JAT, Qiu H, Ottaviani G, Mayweg A, Zhu W, Shen HC, Liu H, Hu T. Kou B, et al. Among authors: young jat. J Med Chem. 2023 Oct 26;66(20):14116-14132. doi: 10.1021/acs.jmedchem.3c01145. Epub 2023 Oct 6. J Med Chem. 2023. PMID: 37801325
Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection.
Zhang W, Guo L, Liu H, Wu G, Shi H, Zhou M, Zhang Z, Kou B, Hu T, Zhou Z, Xu Z, Zhou X, Zhou Y, Tian X, Yang G, Young JAT, Qiu H, Ottaviani G, Xie J, Mayweg AV, Shen HC, Zhu W. Zhang W, et al. Among authors: young jat. J Med Chem. 2023 Mar 23;66(6):4253-4270. doi: 10.1021/acs.jmedchem.3c00173. Epub 2023 Mar 10. J Med Chem. 2023. PMID: 36896968
Discovery of a first-in-class orally available HBV cccDNA inhibitor.
Wang L, Zhu Q, Zhang JD, Zhang Y, Ni X, Xiang K, Jiang J, Li B, Yu Y, Hu H, Zhang M, Wu W, Zeng J, Yan Z, Dai J, Sun K, Zhang X, Chen D, Feng S, Sach-Peltason L, Young JAT, Gao L. Wang L, et al. Among authors: young jat. J Hepatol. 2023 Apr;78(4):742-753. doi: 10.1016/j.jhep.2022.12.014. Epub 2022 Dec 30. J Hepatol. 2023. PMID: 36587899
Toll-Like Receptor 7 Agonist RG7854 Mediates Therapeutic Efficacy and Seroconversion in Woodchucks With Chronic Hepatitis B.
Wildum S, Korolowicz KE, Suresh M, Steiner G, Dai L, Li B, Yon C, De Vera Mudry MC, Regenass-Lechner F, Huang X, Hong X, Murreddu MG, Kallakury BV, Young JAT, Menne S. Wildum S, et al. Among authors: young jat. Front Immunol. 2022 May 23;13:884113. doi: 10.3389/fimmu.2022.884113. eCollection 2022. Front Immunol. 2022. PMID: 35677037 Free PMC article.
Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling.
Johnson JR, Crosby DC, Hultquist JF, Kurland AP, Adhikary P, Li D, Marlett J, Swann J, Hüttenhain R, Verschueren E, Johnson TL, Newton BW, Shales M, Simon VA, Beltrao P, Frankel AD, Marson A, Cox JS, Fregoso OI, Young JAT, Krogan NJ. Johnson JR, et al. Among authors: young jat. Cell Rep. 2022 Apr 12;39(2):110690. doi: 10.1016/j.celrep.2022.110690. Cell Rep. 2022. PMID: 35417684 Free PMC article.
Host RNA quality control as a hepatitis B antiviral target.
Block TM, Young JAT, Javanbakht H, Sofia MJ, Zhou T. Block TM, et al. Among authors: young jat. Antiviral Res. 2021 Feb;186:104972. doi: 10.1016/j.antiviral.2020.104972. Epub 2020 Nov 24. Antiviral Res. 2021. PMID: 33242518 Review.
Accelerated Preclinical Paths to Support Rapid Development of COVID-19 Therapeutics.
Grobler JA, Anderson AS, Fernandes P, Diamond MS, Colvis CM, Menetski JP, Alvarez RM, Young JAT, Carter KL. Grobler JA, et al. Among authors: young jat. Cell Host Microbe. 2020 Nov 11;28(5):638-645. doi: 10.1016/j.chom.2020.09.017. Epub 2020 Oct 1. Cell Host Microbe. 2020. PMID: 33152278 Free PMC article. Review.
The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription.
Langer S, Yin X, Diaz A, Portillo AJ, Gordon DE, Rogers UH, Marlett JM, Krogan NJ, Young JAT, Pache L, Chanda SK. Langer S, et al. Among authors: young jat. Cells. 2020 Sep 1;9(9):2010. doi: 10.3390/cells9092010. Cells. 2020. PMID: 32882949 Free PMC article.
Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon-α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus.
Menne S, Wildum S, Steiner G, Suresh M, Korolowicz K, Balarezo M, Yon C, Murreddu M, Hong X, Kallakury BV, Tucker R, Yang S, Young JAT, Javanbakht H. Menne S, et al. Among authors: young jat. Hepatol Commun. 2020 Apr 22;4(6):916-931. doi: 10.1002/hep4.1502. eCollection 2020 Jun. Hepatol Commun. 2020. PMID: 32490326 Free PMC article.
80 results