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Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.
Stein TD, Anders NJ, DeCarli C, Chan SL, Mattson MP, Johnson JA. Stein TD, et al. Among authors: johnson ja. J Neurosci. 2004 Sep 1;24(35):7707-17. doi: 10.1523/JNEUROSCI.2211-04.2004. J Neurosci. 2004. PMID: 15342738 Free PMC article.
Nrf2, a multi-organ protector?
Lee JM, Li J, Johnson DA, Stein TD, Kraft AD, Calkins MJ, Jakel RJ, Johnson JA. Lee JM, et al. Among authors: johnson ja, johnson da. FASEB J. 2005 Jul;19(9):1061-6. doi: 10.1096/fj.04-2591hyp. FASEB J. 2005. PMID: 15985529
Transthyretin-derived peptides as β-amyloid inhibitors.
Cho PY, Joshi G, Johnson JA, Murphy RM. Cho PY, et al. Among authors: johnson ja. ACS Chem Neurosci. 2014 Jul 16;5(7):542-51. doi: 10.1021/cn500014u. Epub 2014 Apr 9. ACS Chem Neurosci. 2014. PMID: 24689444 Free PMC article.
2,724 results