Johnstone RW - Search Results

1

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

Lalaoui N, Hänggi K, Brumatti G, Chau D, Nguyen NY, Vasilikos L, Spilgies LM, Heckmann DA, Ma C, Ghisi M, Salmon JM, Matthews GM, de Valle E, Moujalled DM, Menon MB, Spall SK, Glaser SP, Richmond J, Lock RB, Condon SM, Gugasyan R, Gaestel M, Guthridge M, Johnstone RW, Munoz L, Wei A, Ekert PG, Vaux DL, Wong WW, Silke J. Lalaoui N, et al. Among authors: johnstone rw. Cancer Cell. 2016 Feb 8;29(2):145-58. doi: 10.1016/j.ccell.2016.01.006. Cancer Cell. 2016. PMID: 26859455 Free article.

2

Apoptosis: a link between cancer genetics and chemotherapy.

Johnstone RW, Ruefli AA, Lowe SW. Johnstone RW, et al. Cell. 2002 Jan 25;108(2):153-64. doi: 10.1016/s0092-8674(02)00625-6. Cell. 2002. PMID: 11832206 Free article. Review.

3

P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation.

Ruefli AA, Tainton KM, Darcy PK, Smyth MJ, Johnstone RW. Ruefli AA, et al. Among authors: johnstone rw. Cell Death Differ. 2002 Nov;9(11):1266-72. doi: 10.1038/sj.cdd.4401081. Cell Death Differ. 2002. PMID: 12404126

4

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

Johnstone RW, Licht JD. Johnstone RW, et al. Cancer Cell. 2003 Jul;4(1):13-8. doi: 10.1016/s1535-6108(03)00165-x. Cancer Cell. 2003. PMID: 12892709 Free article. Review. No abstract available.

5

Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

Peart MJ, Tainton KM, Ruefli AA, Dear AE, Sedelies KA, O'Reilly LA, Waterhouse NJ, Trapani JA, Johnstone RW. Peart MJ, et al. Among authors: johnstone rw. Cancer Res. 2003 Aug 1;63(15):4460-71. Cancer Res. 2003. PMID: 12907619

6

The BH3-only protein bid is dispensable for DNA damage- and replicative stress-induced apoptosis or cell-cycle arrest.

Kaufmann T, Tai L, Ekert PG, Huang DC, Norris F, Lindemann RK, Johnstone RW, Dixit VM, Strasser A. Kaufmann T, et al. Among authors: johnstone rw. Cell. 2007 Apr 20;129(2):423-33. doi: 10.1016/j.cell.2007.03.017. Cell. 2007. PMID: 17448999 Free article.

7

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

Sedelies KA, Ciccone A, Clarke CJ, Oliaro J, Sutton VR, Scott FL, Silke J, Susanto O, Green DR, Johnstone RW, Bird PI, Trapani JA, Waterhouse NJ. Sedelies KA, et al. Among authors: johnstone rw. Cell Death Differ. 2008 Apr;15(4):708-17. doi: 10.1038/sj.cdd.4402300. Epub 2008 Jan 18. Cell Death Differ. 2008. PMID: 18202705

8

Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors.

Algar EM, Muscat A, Dagar V, Rickert C, Chow CW, Biegel JA, Ekert PG, Saffery R, Craig J, Johnstone RW, Ashley DM. Algar EM, et al. Among authors: johnstone rw. PLoS One. 2009;4(2):e4482. doi: 10.1371/journal.pone.0004482. Epub 2009 Feb 16. PLoS One. 2009. PMID: 19221586 Free PMC article.

9

Enhancing the apoptotic and therapeutic effects of HDAC inhibitors.

Frew AJ, Johnstone RW, Bolden JE. Frew AJ, et al. Among authors: johnstone rw. Cancer Lett. 2009 Aug 8;280(2):125-33. doi: 10.1016/j.canlet.2009.02.042. Epub 2009 Apr 8. Cancer Lett. 2009. PMID: 19359091 Review.

10

In vivo activity of combined PI3K/mTOR and MEK inhibition in a Kras(G12D);Pten deletion mouse model of ovarian cancer.

Kinross KM, Brown DV, Kleinschmidt M, Jackson S, Christensen J, Cullinane C, Hicks RJ, Johnstone RW, McArthur GA. Kinross KM, et al. Among authors: johnstone rw. Mol Cancer Ther. 2011 Aug;10(8):1440-9. doi: 10.1158/1535-7163.MCT-11-0240. Epub 2011 Jun 1. Mol Cancer Ther. 2011. PMID: 21632463

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