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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2004 1
2005 2
2007 2
2008 1
2009 1
2010 5
2011 5
2012 2
2013 3
2014 3
2015 2
2016 2
2017 4
2018 1
2019 6
2020 4
2021 3
2022 4
2023 6
2024 2

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53 results

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Page 1
The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading.
Sudhakar N, Yan L, Qiryaqos F, Engstrom LD, Laguer J, Calinisan A, Hebbert A, Waters L, Moya K, Bowcut V, Vegar L, Ketcham JM, Ivetac A, Smith CR, Lawson JD, Rahbaek L, Clarine J, Nguyen N, Saechao B, Parker C, Elliott AJ, Vanderpool D, He L, Hover LD, Fernandez-Banet J, Coma S, Pachter JA, Hallin J, Marx MA, Briere DM, Christensen JG, Olson P, Haling J, Khare S. Sudhakar N, et al. Among authors: pachter ja. Mol Cancer Ther. 2024 Apr 19. doi: 10.1158/1535-7163.MCT-23-0870. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38641404
Preclinical efficacy of RAF/MEK clamp avutometinib in combination with FAK inhibition in low grade serous ovarian cancer.
McNamara B, Demirkiran C, Hartwich TMP, Bellone S, Manavella D, Mutlu L, Greenman M, Zipponi M, Yang-Hartwich Y, Yang K, Ratner E, Schwartz PE, Coma S, Pachter JA, Santin AD. McNamara B, et al. Among authors: pachter ja. Gynecol Oncol. 2024 Feb 9:S0090-8258(24)00043-X. doi: 10.1016/j.ygyno.2024.01.028. Online ahead of print. Gynecol Oncol. 2024. PMID: 38493021
High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.
Arang N, Lubrano S, Ceribelli M, Rigiracciolo DC, Saddawi-Konefka R, Faraji F, Ramirez SI, Kim D, Tosto FA, Stevenson E, Zhou Y, Wang Z, Bogomolovas J, Molinolo AA, Swaney DL, Krogan NJ, Yang J, Coma S, Pachter JA, Aplin AE, Alessi DR, Thomas CJ, Gutkind JS. Arang N, et al. Among authors: pachter ja. Cell Rep Med. 2023 Nov 21;4(11):101244. doi: 10.1016/j.xcrm.2023.101244. Epub 2023 Oct 18. Cell Rep Med. 2023. PMID: 37858338 Free PMC article.
Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Xenograft Model.
Chen SS, Barrientos JC, Ferrer G, King-Richards M, Chen YJ, Ravichandran P, Ibrahim M, Kieso Y, Waters S, Kutok JL, Peluso M, Sharma S, Weaver DT, Pachter JA, Rai KR, Chiorazzi N. Chen SS, et al. Among authors: pachter ja. Clin Cancer Res. 2023 May 15;29(10):1984-1995. doi: 10.1158/1078-0432.CCR-22-2386. Clin Cancer Res. 2023. PMID: 37071496 Free PMC article.
Early path dominance as a principle for neurodevelopment.
Razban RM, Pachter JA, Dill KA, Mujica-Parodi LR. Razban RM, et al. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2218007120. doi: 10.1073/pnas.2218007120. Epub 2023 Apr 13. Proc Natl Acad Sci U S A. 2023. PMID: 37053187 Free PMC article.
Dual Stromal Targeting Sensitizes Pancreatic Adenocarcinoma for Anti-Programmed Cell Death Protein 1 Therapy.
Blair AB, Wang J, Davelaar J, Baker A, Li K, Niu N, Wang J, Shao Y, Funes V, Li P, Pachter JA, Maneval DC, Dezem F, Plummer J, Chan KS, Gong J, Hendifar AE, Pandol SJ, Burkhart R, Zhang Y, Zheng L, Osipov A. Blair AB, et al. Among authors: pachter ja. Gastroenterology. 2022 Nov;163(5):1267-1280.e7. doi: 10.1053/j.gastro.2022.06.027. Epub 2022 Jun 17. Gastroenterology. 2022. PMID: 35718227 Free PMC article.
53 results