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Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy.
Röning T, Magga J, Laitakari A, Halmetoja R, Tapio J, Dimova EY, Szabo Z, Rahtu-Korpela L, Kemppi A, Walkinshaw G, Myllyharju J, Kerkelä R, Koivunen P, Serpi R. Röning T, et al. Among authors: tapio j. J Mol Cell Cardiol. 2022 Mar;164:148-155. doi: 10.1016/j.yjmcc.2021.12.003. Epub 2021 Dec 14. J Mol Cell Cardiol. 2022. PMID: 34919895 Free article.
Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia.
Auvinen J, Tapio J, Karhunen V, Kettunen J, Serpi R, Dimova EY, Gill D, Soininen P, Tammelin T, Mykkänen J, Puukka K, Kähönen M, Raitoharju E, Lehtimäki T, Ala-Korpela M, Raitakari OT, Keinänen-Kiukaanniemi S, Järvelin MR, Koivunen P. Auvinen J, et al. Among authors: tapio j. Sci Adv. 2021 Jul 14;7(29):eabi4822. doi: 10.1126/sciadv.abi4822. Print 2021 Jul. Sci Adv. 2021. PMID: 34261659 Free PMC article.