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Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
Ahire C, Nyul-Toth A, DelFavero J, Gulej R, Faakye JA, Tarantini S, Kiss T, Kuan-Celarier A, Balasubramanian P, Ungvari A, Tarantini A, Nagaraja R, Yan F, Tang Q, Mukli P, Csipo T, Yabluchanskiy A, Campisi J, Ungvari Z, Csiszar A. Ahire C, et al. Among authors: delfavero j. Aging Cell. 2023 Jul;22(7):e13832. doi: 10.1111/acel.13832. Epub 2023 May 26. Aging Cell. 2023. PMID: 37243381 Free PMC article.
Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
Gulej R, Nyúl-Tóth Á, Ahire C, DelFavero J, Balasubramanian P, Kiss T, Tarantini S, Benyo Z, Pacher P, Csik B, Yabluchanskiy A, Mukli P, Kuan-Celarier A, Krizbai IA, Campisi J, Sonntag WE, Csiszar A, Ungvari Z. Gulej R, et al. Among authors: delfavero j. Geroscience. 2023 Oct;45(5):2983-3002. doi: 10.1007/s11357-023-00870-x. Epub 2023 Aug 29. Geroscience. 2023. PMID: 37642933 Free PMC article.
The aging venous system: from varicosities to vascular cognitive impairment.
Molnár AÁ, Nádasy GL, Dörnyei G, Patai BB, Delfavero J, Fülöp GÁ, Kirkpatrick AC, Ungvári Z, Merkely B. Molnár AÁ, et al. Among authors: delfavero j. Geroscience. 2021 Dec;43(6):2761-2784. doi: 10.1007/s11357-021-00475-2. Epub 2021 Nov 11. Geroscience. 2021. PMID: 34762274 Free PMC article. Review.
CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
Zhao Y, Kiss T, DelFavero J, Li L, Li X, Zheng L, Wang J, Jiang C, Shi J, Ungvari Z, Csiszar A, Zhang XA. Zhao Y, et al. Among authors: delfavero j. Geroscience. 2020 Apr;42(2):595-611. doi: 10.1007/s11357-020-00166-4. Epub 2020 Feb 22. Geroscience. 2020. PMID: 32088828 Free PMC article.
Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
Tarantini S, Balasubramanian P, Delfavero J, Csipo T, Yabluchanskiy A, Kiss T, Nyúl-Tóth Á, Mukli P, Toth P, Ahire C, Ungvari A, Benyo Z, Csiszar A, Ungvari Z. Tarantini S, et al. Among authors: delfavero j. Geroscience. 2021 Oct;43(5):2427-2440. doi: 10.1007/s11357-021-00440-z. Epub 2021 Aug 24. Geroscience. 2021. PMID: 34427858 Free PMC article.
Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
Kiss T, Nyúl-Tóth Á, DelFavero J, Balasubramanian P, Tarantini S, Faakye J, Gulej R, Ahire C, Ungvari A, Yabluchanskiy A, Wiley G, Garman L, Ungvari Z, Csiszar A. Kiss T, et al. Among authors: delfavero j. Geroscience. 2022 Apr;44(2):661-681. doi: 10.1007/s11357-022-00521-7. Epub 2022 Jan 31. Geroscience. 2022. PMID: 35098444 Free PMC article.
14 results