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Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104.
Benito J, Shi Y, Szymanska B, Carol H, Boehm I, Lu H, Konoplev S, Fang W, Zweidler-McKay PA, Campana D, Borthakur G, Bueso-Ramos C, Shpall E, Thomas DA, Jordan CT, Kantarjian H, Wilson WR, Lock R, Andreeff M, Konopleva M. Benito J, et al. Among authors: jordan ct. PLoS One. 2011;6(8):e23108. doi: 10.1371/journal.pone.0023108. Epub 2011 Aug 11. PLoS One. 2011. PMID: 21853076 Free PMC article.
Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials.
Woodward WA, Bristow RG, Clarke MF, Coppes RP, Cristofanilli M, Duda DG, Fike JR, Hambardzumyan D, Hill RP, Jordan CT, Milas L, Pajonk F, Curran WJ, Dicker AP, Chen Y. Woodward WA, et al. Among authors: jordan ct. Int J Radiat Oncol Biol Phys. 2009 Aug 1;74(5):1580-91. doi: 10.1016/j.ijrobp.2009.03.047. Epub 2009 Jun 17. Int J Radiat Oncol Biol Phys. 2009. PMID: 19540073
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors.
Zhang X, Song B, Carlino MJ, Li G, Ferchen K, Chen M, Thompson EN, Kain BN, Schnell D, Thakkar K, Kouril M, Jin K, Hay SB, Sen S, Bernardicius D, Ma S, Bennett SN, Croteau J, Salvatori O, Lye MH, Gillen AE, Jordan CT, Singh H, Krause DS, Salomonis N, Grimes HL. Zhang X, et al. Among authors: jordan ct. Nat Immunol. 2024 Apr;25(4):703-715. doi: 10.1038/s41590-024-01782-4. Epub 2024 Mar 21. Nat Immunol. 2024. PMID: 38514887 Free PMC article.
Parthenolide As a Therapeutic for Disseminated Canine Neoplasms.
Schlein LJ, Brill SA, Brady RV, Farrell KB, Rose BJ, Meuten TK, Jordan CT, Thamm DH. Schlein LJ, et al. Among authors: jordan ct. J Pharmacol Exp Ther. 2024 Feb 15;388(3):774-787. doi: 10.1124/jpet.123.001851. J Pharmacol Exp Ther. 2024. PMID: 38135509
Multi-gene measurable residual disease assessed by digital polymerase chain reaction has clinical and biological utility in acute myeloid leukemia patients receiving venetoclax/azacitidine.
Winters AC, Minhajuddin M, Stevens BM, Major A, Bosma G, Abbott D, Miltgen N, Yuan J, Treece AL, Siegele BJ, Ewalt MD, Gutman JA, Jordan CT, Pollyea DA. Winters AC, et al. Among authors: jordan ct. Haematologica. 2023 Dec 14. doi: 10.3324/haematol.2023.283790. Online ahead of print. Haematologica. 2023. PMID: 38105738 Free article.
Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.
Sheth AI, Engel K, Tolison H, Althoff MJ, Amaya ML, Krug A, Young T, Pei S, Patel SB, Minhajuddin M, Winters A, Miller R, Shelton I, St-Germain J, Ling T, Jones C, Raught B, Gillen A, Ransom M, Staggs S, Smith CA, Pollyea DA, Stevens BM, Jordan CT. Sheth AI, et al. Among authors: jordan ct. bioRxiv [Preprint]. 2023 Oct 3:2023.10.02.560330. doi: 10.1101/2023.10.02.560330. bioRxiv. 2023. PMID: 37873284 Free PMC article. Preprint.
A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy.
Pei S, Shelton IT, Gillen AE, Stevens BM, Gasparetto M, Wang Y, Liu L, Liu J, Brunetti TM, Engel K, Staggs S, Showers W, Sheth AI, Amaya ML, Minhajuddin M, Winters A, Patel SB, Tolison H, Krug AE, Young TN, Schowinsky J, McMahon CM, Smith CA, Pollyea DA, Jordan CT. Pei S, et al. Among authors: jordan ct. Cancer Discov. 2023 Sep 6;13(9):2032-2049. doi: 10.1158/2159-8290.CD-22-1297. Cancer Discov. 2023. PMID: 37358260 Free PMC article.
185 results