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Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion.
EMBO Rep. 2023 Nov 6;24(11):e57842. doi: 10.15252/embr.202357842. Epub 2023 Sep 28.
EMBO Rep. 2023.
PMID: 37768718
Free PMC article.
A DNA Origami-Based Biointerface to Interrogate the Spatial Requirements for Sensitized T-Cell Antigen Recognition.
Hellmeier J, Platzer R, Huppa JB, Sevcsik E.
Hellmeier J, et al.
Methods Mol Biol. 2023;2654:277-302. doi: 10.1007/978-1-0716-3135-5_18.
Methods Mol Biol. 2023.
PMID: 37106189
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DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Hellmeier J, Platzer R, Eklund AS, Schlichthaerle T, Karner A, Motsch V, Schneider MC, Kurz E, Bamieh V, Brameshuber M, Preiner J, Jungmann R, Stockinger H, Schütz GJ, Huppa JB, Sevcsik E.
Hellmeier J, et al.
Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2016857118. doi: 10.1073/pnas.2016857118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33468643
Free PMC article.
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Strategies for the Site-Specific Decoration of DNA Origami Nanostructures with Functionally Intact Proteins.
Hellmeier J, Platzer R, Mühlgrabner V, Schneider MC, Kurz E, Schütz GJ, Huppa JB, Sevcsik E.
Hellmeier J, et al.
ACS Nano. 2021 Sep 28;15(9):15057-15068. doi: 10.1021/acsnano.1c05411. Epub 2021 Aug 31.
ACS Nano. 2021.
PMID: 34463486
Free PMC article.
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Balancing the Nanoscale Organization in Multivalent Materials for Functional Inhibition of the Programmed Death-1 Immune Checkpoint.
Paloja K, Weiden J, Hellmeier J, Eklund AS, Reinhardt SCM, Parish IA, Jungmann R, Bastings MMC.
Paloja K, et al. Among authors: hellmeier j.
ACS Nano. 2024 Jan 16;18(2):1381-1395. doi: 10.1021/acsnano.3c06552. Epub 2023 Dec 21.
ACS Nano. 2024.
PMID: 38126310
Free PMC article.
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