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Page 1
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.
Soriano-Baguet L, Grusdat M, Kurniawan H, Benzarti M, Binsfeld C, Ewen A, Longworth J, Bonetti L, Guerra L, Franchina DG, Kobayashi T, Horkova V, Verschueren C, Helgueta S, Gérard D, More TH, Henne A, Dostert C, Farinelle S, Lesur A, Gérardy JJ, Jäger C, Mittelbronn M, Sinkkonen L, Hiller K, Meiser J, Brenner D. Soriano-Baguet L, et al. Among authors: longworth j. Cell Rep. 2023 Mar 28;42(3):112153. doi: 10.1016/j.celrep.2023.112153. Epub 2023 Feb 26. Cell Rep. 2023. PMID: 36848289 Free article.
A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Bonetti L, Horkova V, Longworth J, Guerra L, Kurniawan H, Franchina DG, Soriano-Baguet L, Grusdat M, Spath S, Koncina E, Ewen A, Binsfeld C, Verschueren C, Gérardy JJ, Kobayashi T, Dostert C, Farinelle S, Härm J, Chen Y, Harris IS, Lang PA, Vasiliou V, Waisman A, Letellier E, Becher B, Mittelbronn M, Brenner D. Bonetti L, et al. Among authors: longworth j. bioRxiv [Preprint]. 2023 Jul 7:2023.07.06.547932. doi: 10.1101/2023.07.06.547932. bioRxiv. 2023. PMID: 37489135 Free PMC article. Preprint.
A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma.
Gureghian V, Herbst H, Kozar I, Mihajlovic K, Malod-Dognin N, Ceddia G, Angeli C, Margue C, Randic T, Philippidou D, Nomigni MT, Hemedan A, Tranchevent LC, Longworth J, Bauer M, Badkas A, Gaigneaux A, Muller A, Ostaszewski M, Tolle F, Pržulj N, Kreis S. Gureghian V, et al. Among authors: longworth j. Cancer Gene Ther. 2023 Oct;30(10):1330-1345. doi: 10.1038/s41417-023-00640-z. Epub 2023 Jul 7. Cancer Gene Ther. 2023. PMID: 37420093 Free PMC article.
A protein quality control pathway regulated by linear ubiquitination.
van Well EM, Bader V, Patra M, Sánchez-Vicente A, Meschede J, Furthmann N, Schnack C, Blusch A, Longworth J, Petrasch-Parwez E, Mori K, Arzberger T, Trümbach D, Angersbach L, Showkat C, Sehr DA, Berlemann LA, Goldmann P, Clement AM, Behl C, Woerner AC, Saft C, Wurst W, Haass C, Ellrichmann G, Gold R, Dittmar G, Hipp MS, Hartl FU, Tatzelt J, Winklhofer KF. van Well EM, et al. Among authors: longworth j. EMBO J. 2019 May 2;38(9):e100730. doi: 10.15252/embj.2018100730. Epub 2019 Mar 18. EMBO J. 2019. PMID: 30886048 Free PMC article.
12 results