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Page 1
Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.
Champiré A, Berabez R, Braka A, Cosson A, Corret J, Girardin C, Serrano A, Aci-Sèche S, Bonnet P, Josselin B, Brindeau P, Ruchaud S, Leguevel R, Chatterjee D, Mathea S, Knapp S, Brion R, Verrecchia F, Vallée B, Plé K, Bénédetti H, Routier S. Champiré A, et al. Among authors: josselin b. Eur J Med Chem. 2024 Apr 9;271:116391. doi: 10.1016/j.ejmech.2024.116391. Online ahead of print. Eur J Med Chem. 2024. PMID: 38669909
Synthesis and biological evaluation of 1H-pyrrolo[3,2-g]isoquinolines.
Defois M, Josselin B, Brindeau P, Krämer A, Knapp S, Anizon F, Giraud F, Ruchaud S, Moreau P. Defois M, et al. Among authors: josselin b. Bioorg Med Chem. 2024 Feb 15;100:117619. doi: 10.1016/j.bmc.2024.117619. Epub 2024 Feb 1. Bioorg Med Chem. 2024. PMID: 38320389
Imidazo[1,2-a]quinazolines as novel, potent EGFR-TK inhibitors: Design, synthesis, bioactivity evaluation, and in silico studies.
Hasanvand Z, Oghabi Bakhshaiesh T, Peytam F, Firoozpour L, Hosseinzadeh E, Motahari R, Moghimi S, Nazeri E, Toolabi M, Momeni F, Bijanzadeh H, Khalaj A, Baratte B, Josselin B, Robert T, Bach S, Esmaeili R, Foroumadi A. Hasanvand Z, et al. Among authors: josselin b. Bioorg Chem. 2023 Apr;133:106383. doi: 10.1016/j.bioorg.2023.106383. Epub 2023 Jan 20. Bioorg Chem. 2023. PMID: 36764231
Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation.
Elie J, Feizbakhsh O, Desban N, Josselin B, Baratte B, Bescond A, Duez J, Fant X, Bach S, Marie D, Place M, Ben Salah S, Chartier A, Berteina-Raboin S, Chaikuad A, Knapp S, Carles F, Bonnet P, Buron F, Routier S, Ruchaud S. Elie J, et al. Among authors: josselin b. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1840-1853. doi: 10.1080/14756366.2020.1825408. J Enzyme Inhib Med Chem. 2020. PMID: 33040634 Free PMC article.
Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1.
Benchekroun M, Ermolenko L, Tran MQ, Vagneux A, Nedev H, Delehouzé C, Souab M, Baratte B, Josselin B, Iorga BI, Ruchaud S, Bach S, Al-Mourabit A. Benchekroun M, et al. Among authors: josselin b. Eur J Med Chem. 2020 Sep 1;201:112337. doi: 10.1016/j.ejmech.2020.112337. Epub 2020 Jun 25. Eur J Med Chem. 2020. PMID: 32659605
16 results