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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.
Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R, Yu H. Niu G, et al. Among authors: jove r. Oncogene. 2002 Mar 27;21(13):2000-8. doi: 10.1038/sj.onc.1205260. Oncogene. 2002. PMID: 11960372
STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues.
Velichko S, Wagner TC, Turkson J, Jove R, Croze E. Velichko S, et al. Among authors: jove r. J Biol Chem. 2002 Sep 20;277(38):35635-41. doi: 10.1074/jbc.M204578200. Epub 2002 Jun 24. J Biol Chem. 2002. PMID: 12105218 Free article.
Stat3 regulates genes common to both wound healing and cancer.
Dauer DJ, Ferraro B, Song L, Yu B, Mora L, Buettner R, Enkemann S, Jove R, Haura EB. Dauer DJ, et al. Among authors: jove r. Oncogene. 2005 May 12;24(21):3397-408. doi: 10.1038/sj.onc.1208469. Oncogene. 2005. PMID: 15735721
STATs in oncogenesis.
Bowman T, Garcia R, Turkson J, Jove R. Bowman T, et al. Among authors: jove r. Oncogene. 2000 May 15;19(21):2474-88. doi: 10.1038/sj.onc.1203527. Oncogene. 2000. PMID: 10851046 Review.
242 results