Joyce JA - Search Results

1

Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis.

Klemm F, Möckl A, Salamero-Boix A, Alekseeva T, Schäffer A, Schulz M, Niesel K, Maas RR, Groth M, Elie BT, Bowman RL, Hegi ME, Daniel RT, Zeiner PS, Zinke J, Harter PN, Plate KH, Joyce JA, Sevenich L. Klemm F, et al. Among authors: joyce ja. Nat Cancer. 2021 Oct;2(10):1086-1101. doi: 10.1038/s43018-021-00254-0. Epub 2021 Oct 18. Nat Cancer. 2021. PMID: 35121879

2

Microenvironmental regulation of metastasis.

Joyce JA, Pollard JW. Joyce JA, et al. Nat Rev Cancer. 2009 Apr;9(4):239-52. doi: 10.1038/nrc2618. Epub 2008 Mar 12. Nat Rev Cancer. 2009. PMID: 19279573 Free PMC article. Review.

3

Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.

Elie BT, Gocheva V, Shree T, Dalrymple SA, Holsinger LJ, Joyce JA. Elie BT, et al. Among authors: joyce ja. Biochimie. 2010 Nov;92(11):1618-24. doi: 10.1016/j.biochi.2010.04.023. Epub 2010 May 4. Biochimie. 2010. PMID: 20447439 Free PMC article.

4

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer.

Shree T, Olson OC, Elie BT, Kester JC, Garfall AL, Simpson K, Bell-McGuinn KM, Zabor EC, Brogi E, Joyce JA. Shree T, et al. Among authors: joyce ja. Genes Dev. 2011 Dec 1;25(23):2465-79. doi: 10.1101/gad.180331.111. Genes Dev. 2011. PMID: 22156207 Free PMC article.

5

CSF-1R inhibition alters macrophage polarization and blocks glioma progression.

Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. Pyonteck SM, et al. Among authors: joyce ja. Nat Med. 2013 Oct;19(10):1264-72. doi: 10.1038/nm.3337. Epub 2013 Sep 22. Nat Med. 2013. PMID: 24056773 Free PMC article.

6

Microenvironmental regulation of tumor progression and metastasis.

Quail DF, Joyce JA. Quail DF, et al. Among authors: joyce ja. Nat Med. 2013 Nov;19(11):1423-37. doi: 10.1038/nm.3394. Nat Med. 2013. PMID: 24202395 Free PMC article. Review.

7

Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma.

Bowman RL, Joyce JA. Bowman RL, et al. Among authors: joyce ja. Immunotherapy. 2014;6(6):663-6. doi: 10.2217/imt.14.48. Immunotherapy. 2014. PMID: 25041027 No abstract available.

8

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S.

Sevenich L, Bowman RL, Mason SD, Quail DF, Rapaport F, Elie BT, Brogi E, Brastianos PK, Hahn WC, Holsinger LJ, Massagué J, Leslie CS, Joyce JA. Sevenich L, et al. Among authors: joyce ja. Nat Cell Biol. 2014 Sep;16(9):876-88. doi: 10.1038/ncb3011. Epub 2014 Aug 3. Nat Cell Biol. 2014. PMID: 25086747 Free PMC article.

9

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. Akkari L, et al. Among authors: joyce ja. Genes Dev. 2014 Oct 1;28(19):2134-50. doi: 10.1101/gad.249599.114. Genes Dev. 2014. PMID: 25274726 Free PMC article.

10

Pericellular proteolysis in cancer.

Sevenich L, Joyce JA. Sevenich L, et al. Among authors: joyce ja. Genes Dev. 2014 Nov 1;28(21):2331-47. doi: 10.1101/gad.250647.114. Genes Dev. 2014. PMID: 25367033 Free PMC article. Review.

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