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Page 1
MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities.
Rohrberg J, Van de Mark D, Amouzgar M, Lee JV, Taileb M, Corella A, Kilinc S, Williams J, Jokisch ML, Camarda R, Balakrishnan S, Shankar R, Zhou A, Chang AN, Chen B, Rugo HS, Dumont S, Goga A. Rohrberg J, et al. Cell Rep. 2020 Mar 10;30(10):3368-3382.e7. doi: 10.1016/j.celrep.2020.02.041. Cell Rep. 2020. PMID: 32160543 Free PMC article.
The Plasticity of the Hsp90 Co-chaperone System.
Sahasrabudhe P, Rohrberg J, Biebl MM, Rutz DA, Buchner J. Sahasrabudhe P, et al. Among authors: rohrberg j. Mol Cell. 2017 Sep 21;67(6):947-961.e5. doi: 10.1016/j.molcel.2017.08.004. Epub 2017 Sep 7. Mol Cell. 2017. PMID: 28890336 Free article.
The chaperone Hsp90: changing partners for demanding clients.
Röhl A, Rohrberg J, Buchner J. Röhl A, et al. Among authors: rohrberg j. Trends Biochem Sci. 2013 May;38(5):253-62. doi: 10.1016/j.tibs.2013.02.003. Epub 2013 Mar 16. Trends Biochem Sci. 2013. PMID: 23507089 Review.
Regulated structural transitions unleash the chaperone activity of αB-crystallin.
Peschek J, Braun N, Rohrberg J, Back KC, Kriehuber T, Kastenmüller A, Weinkauf S, Buchner J. Peschek J, et al. Among authors: rohrberg j. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3780-9. doi: 10.1073/pnas.1308898110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043785 Free PMC article.
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer.
Shah KN, Bhatt R, Rotow J, Rohrberg J, Olivas V, Wang VE, Hemmati G, Martins MM, Maynard A, Kuhn J, Galeas J, Donnella HJ, Kaushik S, Ku A, Dumont S, Krings G, Haringsma HJ, Robillard L, Simmons AD, Harding TC, McCormick F, Goga A, Blakely CM, Bivona TG, Bandyopadhyay S. Shah KN, et al. Among authors: rohrberg j. Nat Med. 2019 Jan;25(1):111-118. doi: 10.1038/s41591-018-0264-7. Epub 2018 Nov 26. Nat Med. 2019. PMID: 30478424 Free PMC article.
PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression.
Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, Corella AN, Eyob H, Kessenbrock K, Lawson DA, Marsh LA, Anderton BN, Rohrberg J, Kunder R, Bazarov AV, Yaswen P, McManus MT, Rugo HS, Werb Z, Goga A. Horiuchi D, et al. Among authors: rohrberg j. Nat Med. 2016 Nov;22(11):1321-1329. doi: 10.1038/nm.4213. Epub 2016 Oct 24. Nat Med. 2016. PMID: 27775705 Free PMC article.