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Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations.
Akbergenov R, Duscha S, Fritz AK, Juskeviciene R, Oishi N, Schmitt K, Shcherbakov D, Teo Y, Boukari H, Freihofer P, Isnard-Petit P, Oettinghaus B, Frank S, Thiam K, Rehrauer H, Westhof E, Schacht J, Eckert A, Wolfer D, Böttger EC. Akbergenov R, et al. Among authors: juskeviciene r. EMBO Rep. 2018 Nov;19(11):e46193. doi: 10.15252/embr.201846193. Epub 2018 Sep 20. EMBO Rep. 2018. PMID: 30237157 Free PMC article.
Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis.
Shcherbakov D, Teo Y, Boukari H, Cortes-Sanchon A, Mantovani M, Osinnii I, Moore J, Juskeviciene R, Brilkova M, Duscha S, Kumar HS, Laczko E, Rehrauer H, Westhof E, Akbergenov R, Böttger EC. Shcherbakov D, et al. Among authors: juskeviciene r. Commun Biol. 2019 Oct 17;2:381. doi: 10.1038/s42003-019-0626-9. eCollection 2019. Commun Biol. 2019. PMID: 31637312 Free PMC article.
Synthesis and Antiribosomal Activities of 4'-O-, 6'-O-, 4″-O-, 4',6'-O- and 4″,6″-O-Derivatives in the Kanamycin Series Indicate Differing Target Selectivity Patterns between the 4,5- and 4,6-Series of Disubstituted 2-Deoxystreptamine Aminoglycoside Antibiotics.
Kato T, Yang G, Teo Y, Juskeviciene R, Perez-Fernandez D, Shinde HM, Salian S, Bernet B, Vasella A, Böttger EC, Crich D. Kato T, et al. Among authors: juskeviciene r. ACS Infect Dis. 2015 Oct 9;1(10):479-86. doi: 10.1021/acsinfecdis.5b00069. Epub 2015 Aug 6. ACS Infect Dis. 2015. PMID: 27623314