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Translation stress and collided ribosomes are co-activators of cGAS.
Wan L, Juszkiewicz S, Blears D, Bajpe PK, Han Z, Faull P, Mitter R, Stewart A, Snijders AP, Hegde RS, Svejstrup JQ. Wan L, et al. Among authors: juszkiewicz s. Mol Cell. 2021 Jul 1;81(13):2808-2822.e10. doi: 10.1016/j.molcel.2021.05.018. Epub 2021 Jun 9. Mol Cell. 2021. PMID: 34111399 Free PMC article.
Quality Control of Orphaned Proteins.
Juszkiewicz S, Hegde RS. Juszkiewicz S, et al. Mol Cell. 2018 Aug 2;71(3):443-457. doi: 10.1016/j.molcel.2018.07.001. Mol Cell. 2018. PMID: 30075143 Free PMC article. Review.
The ASC-1 Complex Disassembles Collided Ribosomes.
Juszkiewicz S, Speldewinde SH, Wan L, Svejstrup JQ, Hegde RS. Juszkiewicz S, et al. Mol Cell. 2020 Aug 20;79(4):603-614.e8. doi: 10.1016/j.molcel.2020.06.006. Epub 2020 Jun 23. Mol Cell. 2020. PMID: 32579943 Free PMC article.
Mechanism of ribosome stalling during translation of a poly(A) tail.
Chandrasekaran V, Juszkiewicz S, Choi J, Puglisi JD, Brown A, Shao S, Ramakrishnan V, Hegde RS. Chandrasekaran V, et al. Among authors: juszkiewicz s. Nat Struct Mol Biol. 2019 Dec;26(12):1132-1140. doi: 10.1038/s41594-019-0331-x. Epub 2019 Nov 25. Nat Struct Mol Biol. 2019. PMID: 31768042 Free PMC article.
ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Juszkiewicz S, Chandrasekaran V, Lin Z, Kraatz S, Ramakrishnan V, Hegde RS. Juszkiewicz S, et al. Mol Cell. 2018 Nov 1;72(3):469-481.e7. doi: 10.1016/j.molcel.2018.08.037. Epub 2018 Oct 4. Mol Cell. 2018. PMID: 30293783 Free PMC article.
EMC Is Required to Initiate Accurate Membrane Protein Topogenesis.
Chitwood PJ, Juszkiewicz S, Guna A, Shao S, Hegde RS. Chitwood PJ, et al. Among authors: juszkiewicz s. Cell. 2018 Nov 29;175(6):1507-1519.e16. doi: 10.1016/j.cell.2018.10.009. Epub 2018 Nov 8. Cell. 2018. PMID: 30415835 Free PMC article.
The architecture of EMC reveals a path for membrane protein insertion.
O'Donnell JP, Phillips BP, Yagita Y, Juszkiewicz S, Wagner A, Malinverni D, Keenan RJ, Miller EA, Hegde RS. O'Donnell JP, et al. Among authors: juszkiewicz s. Elife. 2020 May 27;9:e57887. doi: 10.7554/eLife.57887. Elife. 2020. PMID: 32459176 Free PMC article.
12 results