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Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis.
Kaaij MH, van Tok MN, Blijdorp IC, Ambarus CA, Stock M, Pots D, Knaup VL, Armaka M, Christodoulou-Vafeiadou E, van Melsen TK, Masdar H, Eskes HJPP, Yeremenko NG, Kollias G, Schett G, Tas SW, van Duivenvoorde LM, Baeten DLP. Kaaij MH, et al. J Exp Med. 2020 Oct 5;217(10):e20200288. doi: 10.1084/jem.20200288. J Exp Med. 2020. PMID: 32662821 Free PMC article.
Overexpression of Transmembrane TNF Drives Development of Ectopic Lymphoid Structures in the Bone Marrow and B Cell Lineage Alterations in Experimental Spondyloarthritis.
Kaaij MH, Rip J, Jeucken KCM, Kan YY, van Rooijen CCN, Saris J, Pots D, Frey S, Grootjans J, Schett G, van Duivenvoorde LM, Nolte MA, Hendriks RW, Corneth OBJ, van Hamburg JP, Baeten DLP, Tas SW. Kaaij MH, et al. J Immunol. 2021 Nov 1;207(9):2337-2346. doi: 10.4049/jimmunol.2100512. Epub 2021 Sep 24. J Immunol. 2021. PMID: 34561228